Advances in heterocycles as DNA intercalating cancer drugs

A Das, BK Banik - Physical Sciences Reviews, 2023 - degruyter.com
The insertion of a molecule between the bases of DNA is known as intercalation. A molecule
is able to interact with DNA in different ways. DNA intercalators are generally aromatic …

A Minor Groove Binder with Significant Cytotoxicity on Human Lung Cancer Cells: The Potential of Hesperetin Functionalised Silver Nanoparticles

A Raj, RK Thomas, L Vidya, S Neelima… - Journal of …, 2023 - Springer
Natural drug functionalised silver (Ag) nanoparticles (NPs) have gained significant interest
in pharmacology related applications due to their therapeutic efficiency. We have …

Dinuclear platinum (II) complexes as the pattern for phosphate backbone binding: a new perspective for recognition of binding modes to DNA

AA Franich, IS Đorđević, MD Živković… - JBIC Journal of …, 2022 - Springer
The mechanism of action of most approved drugs in use today is based on their binding to
specific proteins or DNA. One of the achievements of this research is a new perspective for …

Spectroscopic study of interaction of various GC-content DNA with Hoechst 33258 depending on Na+ concentration

PO Vardevanyan, MA Parsadanyan… - Journal of …, 2021 - Taylor & Francis
Full article: Spectroscopic study of interaction of various GC-content DNA with Hoechst 33258
depending on Na+ concentration Skip to Main Content Taylor and Francis Online homepage …

STUDY OF STRUCTURAL TRANSITIONS OF COMPLEXES OF DIFFERENT LIGANDS WITH DNA AND BSA

PH Vardevanyan, NR Petrosyan - … of the YSU B: Chemical and …, 2022 - journals.ysu.am
Structural transitions of DNA and bovine serum albumin (BSA) and their complexes with
methylene blue (MB) and Hoechst 33258 (H33258) by UV-denaturation method have been …

[PDF][PDF] Peculiarities of acridine orange binding with DNA

PO Vardevanyan, AP Antonyan… - Հայաստանի …, 2016 - 93.187.165.86
Materials and methods. Calf thymus DNA–D-1501 (“Sigma”, USA), AO (“Sigma”, USA),
NaCl, Na-citrate, EDTA (ethylenediamintetraacetate)(chemically pure) were used in …

STUDY OF COMPARATIVE INTERACTION OF ETHIDIUM BROMIDE AND MITOXANTRONE WITH NUCLEIC ACIDS

AP Antonyan, MA Torosyan… - Proceedings of the YSU …, 2018 - journals.ysu.am
The study of joint binding of intercalating compounds–ethidium bromide (EtBr) and
mitoxantrone (MTX) with double-stranded DNA (ds-DNA) and poly (rA)-poly (rU)(ds-RNA) …

INTERACTION OF DIFFERENT INTERCALATORS WITH DNA IN THREE-COMPONENT SYSTEMS.

AP Antonyan, MA Torosyan… - Ajastan …, 2018 - search.ebscohost.com
The study of the joint binding of the intercalating compounds ethidium bromide (EtBr) and
mitoxantrone (MTX) with DNA has been carried out. Melting parameters of the three …

Comparative Study of Ethidium Bromide Interaction with Synthetic Polynucleotides ds-Poly (rA)-Poly (rU) and ds-Poly (dA)-Poly (dT)

MA Parsadanyan - Proceedings of the YSU B: Chemical and …, 2019 - journals.ysu.am
A comparative study on the interaction of classical intercalator ethidium bromide (EtBr) with
different nucleic acids (NA) has been carried out. EtBr was revealed to preferentially bind to …

Study of binding peculiarities of ethidium bromide and methylene blue with double-stranded RNA

MA Parsadanyan - Proceedings of the YSU B: Chemical and …, 2020 - journals.ysu.am
The paper presents the results of studies on the interaction of intercalators ethidium bromide
(EtBr) and methylene blue (MB) with synthetic double-stranded (ds) ribonucleotide ds-poly …