Photodynamic therapy: a novel approach for head and neck cancer treatment with focusing on oral cavity

KS Kazemi, P Kazemi, H Mivehchi, K Nasiri… - Biological Procedures …, 2024 - Springer
Oral cancers, specifically oral squamous cell carcinoma (OSCC), pose a significant global
health challenge, with high incidence and mortality rates. Conventional treatments such as …

[HTML][HTML] Devices and methods for dosimetry of personalized photodynamic therapy of tumors: a review on recent trends

P Alekseeva, V Makarov, K Efendiev, A Shiryaev… - Cancers, 2024 - mdpi.com
Simple Summary The current devices and methods for dosimetry of personalized
photodynamic therapy of tumors have several disadvantages. For instance, they are unable …

Combined radiation strategies for novel and enhanced cancer treatment

G Kareliotis, I Tremi, M Kaitatzi, E Drakaki… - … Journal of Radiation …, 2020 - Taylor & Francis
Numerous studies focus on cancer therapy worldwide, and although many advances have
been recorded, the complexity of the disease dictates thinking out of the box to confront it …

Laser-assisted aPDT protocols in randomized controlled clinical trials in dentistry: a systematic review

V Mylona, E Anagnostaki, S Parker, M Cronshaw… - Dentistry Journal, 2020 - mdpi.com
Background: Antimicrobial photodynamic therapy (aPDT) has been proposed as an effective
alternative method for the adjunctive treatment of all classes of oral infections. The …

Singlet oxygen model evaluation of interstitial photodynamic therapy with 5-aminolevulinic acid for malignant brain tumor

A Izumoto, T Nishimura, H Hazama… - Journal of …, 2020 - spiedigitallibrary.org
Interstitial photodynamic therapy (iPDT) with 5-aminolevulinic acid (ALA) is a possible
alternative treatment for malignant brain tumors. Further evaluation is, however, required …

Emerging therapeutic targets in oncologic photodynamic therapy

G Manda, ME Hinescu, IV Neagoe… - Current …, 2018 - ingentaconnect.com
Background: Reactive oxygen species sustain tumorigenesis and cancer progression
through deregulated redox signalling which also sensitizes cancer cells to therapy …

Non-ionizing, laser radiation in Theranostics: The need for dosimetry and the role of Medical Physics

M Makropoulou, G Kareliotis, E Spyratou, E Drakaki… - Physica Medica, 2019 - Elsevier
The discovery of coherent laser light in 1960 shifted and expanded the biomedical
applications of radiation to the non-ionizing part of the electromagnetic spectrum. As in the …

[HTML][HTML] Computational modelling of the therapeutic outputs of photodynamic therapy on spheroid-on-chip models

H Kazempour, F Teymouri, M Khatami… - … of Photochemistry and …, 2024 - Elsevier
Photodynamic therapy (PDT) is a medical radio chemotherapeutic method that uses light,
photosensitizing agents, and oxygen to produce cytotoxic compounds, which eliminate …

Analysis and data-based modeling of the photochemical reaction dynamics of the induced singlet oxygen in light therapies

T Wang, J Dong, G Zhang - IEEE Transactions on Biomedical …, 2022 - ieeexplore.ieee.org
Objective: The macroscopic singlet oxygen (MSO) model for quantifying the light-induced
singlet oxygen () always contain a set of nonlinear dynamic equations and therefore are …

In Silico, Combined Plasmonic Photothermal and Photodynamic Therapy in Mice

G Kareliotis, E Chronopoulou… - Journal of …, 2022 - mdpi.com
Plasmonic photothermal and photodynamic therapy (PPTT and PDT, respectively) are two
cancer treatments that have the potential to be combined in a synergistic scheme. The aim of …