Towards a deeper understanding of the vaginal microbiota

M France, M Alizadeh, S Brown, B Ma, J Ravel - Nature microbiology, 2022 - nature.com
The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources …

Healthy vaginal microbiota and influence of probiotics across the female life span

L Lehtoranta, R Ala-Jaakkola, A Laitila… - Frontiers in …, 2022 - frontiersin.org
Vaginal microbiota plays a central role in women's health and reproduction. Vaginal
microbiota is dynamic and shaped by hormonal shifts in each stage of a woman's life from …

Oral administration of maternal vaginal microbes at birth to restore gut microbiome development in infants born by caesarean section: A pilot randomised placebo …

BC Wilson, ÉM Butler, CP Grigg, JGB Derraik… - …, 2021 - thelancet.com
Background Birth by caesarean section (CS) is associated with aberrant gut microbiome
development and greater disease susceptibility later in life. We investigated whether oral …

Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation

SM Bloom, NA Mafunda, BM Woolston… - Nature …, 2022 - nature.com
Vaginal microbiota composition affects many facets of reproductive health. Lactobacillus
iners-dominated microbial communities are associated with poorer outcomes, including …

A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration

J Reynoso-García, AE Miranda-Santiago… - Frontiers in Systems …, 2022 - frontiersin.org
Humans are supra-organisms co-evolved with microbial communities (Prokaryotic and
Eukaryotic), named the microbiome. These microbiomes supply essential ecosystem …

Vaginotypes of the human vaginal microbiome

L Mancabelli, C Tarracchini, C Milani… - Environmental …, 2021 - Wiley Online Library
The human vaginal environment harbours a community of bacteria that plays an important
role in maintaining vaginal health and in protecting this environment from various urogenital …

Recent advances in understanding of multifaceted changes in the vaginal microenvironment: implications in vaginal health and therapeutics

S Das, MJ Bhattacharjee, AK Mukherjee… - Critical Reviews in …, 2023 - Taylor & Francis
The vagina endures multifaceted changes from neonatal to menopausal phases due to
hormonal flux, metabolite deposition, and microbial colonization. These features have …

New perspectives into the vaginal microbiome with systems biology

CY Lee, LR Dillard, JA Papin, KB Arnold - Trends in Microbiology, 2023 - cell.com
The vaginal microbiome (VMB) is critical to female reproductive health; however, the
mechanisms associated with optimal and non-optimal states remain poorly understood due …

The cervical microbiota of Hispanics living in Puerto Rico is nonoptimal regardless of HPV status

D Vargas-Robles, J Romaguera, I Alvarado-Velez… - Msystems, 2023 - Am Soc Microbiol
The cervicovaginal microbiota is influenced by host physiology, immunology, lifestyle, and
ethnicity. We hypothesized that there would be differences in the cervicovaginal microbiota …

[HTML][HTML] Cervicovaginal microbiome, high-risk HPV infection and cervical cancer: Mechanisms and therapeutic potential

R Huang, Z Liu, T Sun, L Zhu - Microbiological Research, 2024 - Elsevier
The microbiota in the female genital tract is an intricate assembly of diverse aerobic,
anaerobic, and microaerophilic microorganisms, which share the space within the …