Therapeutic pipeline in nonalcoholic steatohepatitis
R Vuppalanchi, M Noureddin, N Alkhouri… - Nature Reviews …, 2021 - nature.com
Our understanding of nonalcoholic fatty liver disease pathophysiology continues to advance
rapidly. Accordingly, the field has moved from describing the clinical phenotype through the …
rapidly. Accordingly, the field has moved from describing the clinical phenotype through the …
Complications, morbidity and mortality of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is an increasingly recognized public health
problem, affecting up to a quarter of the world's adult population. The burden of NAFLD is …
problem, affecting up to a quarter of the world's adult population. The burden of NAFLD is …
The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease
Metabolic associated fatty liver disease (MAFLD) is the principal worldwide cause of liver
disease and affects nearly a quarter of the global population. The objective of this work was …
disease and affects nearly a quarter of the global population. The objective of this work was …
Selonsertib for patients with bridging fibrosis or compensated cirrhosis due to NASH: results from randomized phase III STELLAR trials
SA Harrison, VWS Wong, T Okanoue, N Bzowej… - Journal of …, 2020 - Elsevier
Background & Aims Apoptosis signal-regulating kinase 1 (ASK1) plays a key role in
hepatocyte injury, inflammation, and fibrosis in non-alcoholic steatohepatitis (NASH). We …
hepatocyte injury, inflammation, and fibrosis in non-alcoholic steatohepatitis (NASH). We …
Geographical similarity and differences in the burden and genetic predisposition of NAFLD
NAFLD has become a major public health problem for more than 2 decades with a growing
prevalence in parallel with the epidemic of obesity and type 2 diabetes (T2D). The disease …
prevalence in parallel with the epidemic of obesity and type 2 diabetes (T2D). The disease …
Nonalcoholic fatty liver disease burden: Australia, 2019–2030
LA Adams, SK Roberts, SI Strasser… - Journal of …, 2020 - Wiley Online Library
Abstract Background and Aim Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic
steatohepatitis (NASH) account for a large and growing proportion of liver disease burden …
steatohepatitis (NASH) account for a large and growing proportion of liver disease burden …
The epidemiology of NAFLD in Mainland China with analysis by adjusted gross regional domestic product: a meta-analysis
Background Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver
disease worldwide. This study aimed to estimate the prevalence, incidence, and outcome of …
disease worldwide. This study aimed to estimate the prevalence, incidence, and outcome of …
Estimating global prevalence, incidence, and outcomes of non-alcoholic fatty liver disease from 2000 to 2021: systematic review and meta-analysis
J Liu, Y Tian, X Fu, C Mu, M Yao, Y Ni, Y Liu… - Chinese Medical …, 2022 - mednexus.org
Background: The increasing burden of non-alcoholic fatty liver disease (NAFLD) worldwide
imposes an emerging public health issue. We perform the current study to estimate the …
imposes an emerging public health issue. We perform the current study to estimate the …
[HTML][HTML] Metabolic associated fatty liver disease: Addressing a new era in liver transplantation
MG Gill, A Majumdar - World journal of hepatology, 2020 - ncbi.nlm.nih.gov
Metabolic associated fatty liver disease (MAFLD), previously termed non-alcoholic fatty liver
disease, is the leading global cause of liver disease and is fast becoming the most common …
disease, is the leading global cause of liver disease and is fast becoming the most common …
The effect of diet and exercise interventions on body composition in liver cirrhosis: a systematic review
HE Johnston, TG Takefala, JT Kelly, SE Keating… - Nutrients, 2022 - mdpi.com
Alterations in body composition, in particular sarcopenia and sarcopenic obesity, are
complications of liver cirrhosis associated with adverse outcomes. This systematic review …
complications of liver cirrhosis associated with adverse outcomes. This systematic review …