Oxidative stress in ageing and chronic degenerative pathologies: molecular mechanisms involved in counteracting oxidative stress and chronic inflammation
TS Leyane, SW Jere, NN Houreld - International journal of molecular …, 2022 - mdpi.com
Ageing and chronic degenerative pathologies demonstrate the shared characteristics of
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …
Pathophysiology of hypoxic–ischemic encephalopathy: a review of the past and a view on the future
P Greco, G Nencini, I Piva, M Scioscia, CA Volta… - Acta Neurologica …, 2020 - Springer
Hypoxic–ischemic encephalopathy, also referred as HIE, is a type of brain injury or damage
that is caused by a lack of oxygen to the brain during neonatal period. The incidence is …
that is caused by a lack of oxygen to the brain during neonatal period. The incidence is …
Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy?
B Fleiss, P Gressens - The Lancet Neurology, 2012 - thelancet.com
Cerebral palsy is caused by injury or developmental disturbances to the immature brain and
leads to substantial motor, cognitive, and learning deficits. In addition to developmental …
leads to substantial motor, cognitive, and learning deficits. In addition to developmental …
Neuroprotective strategies after neonatal hypoxic ischemic encephalopathy
BJ Dixon, C Reis, WM Ho, J Tang… - International journal of …, 2015 - mdpi.com
Neonatal hypoxic ischemic encephalopathy (HIE) is a devastating disease that primarily
causes neuronal and white matter injury and is among the leading cause of death among …
causes neuronal and white matter injury and is among the leading cause of death among …
Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain
RH Andres, N Horie, W Slikker, H Keren-Gill, K Zhan… - Brain, 2011 - academic.oup.com
Stem cell transplantation promises new hope for the treatment of stroke although significant
questions remain about how the grafted cells elicit their effects. One hypothesis is that …
questions remain about how the grafted cells elicit their effects. One hypothesis is that …
Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain
Reprogramming of adult human somatic cells to induced pluripotent stem cells (iPSCs) is a
novel approach to produce patient-specific cells for autologous transplantation. Whether …
novel approach to produce patient-specific cells for autologous transplantation. Whether …
Neural stem cell therapies and hypoxic-ischemic brain injury
Hypoxic-ischemic brain injury is a significant cause of morbidity and mortality in the adult as
well as in the neonate. Extensive pre-clinical studies have shown promising therapeutic …
well as in the neonate. Extensive pre-clinical studies have shown promising therapeutic …
Human induced pluripotent stem cell-derived cortical neurons integrate in stroke-injured cortex and improve functional recovery
Stem cell-based approaches to restore function after stroke through replacement of dead
neurons require the generation of specific neuronal subtypes. Loss of neurons in the …
neurons require the generation of specific neuronal subtypes. Loss of neurons in the …
Therapeutic plasticity of neural stem cells
L Ottoboni, B von Wunster, G Martino - Frontiers in neurology, 2020 - frontiersin.org
Neural stem cells (NSCs) have garnered significant scientific and commercial interest in the
last 15 years. Given their plasticity, defined as the ability to develop into different phenotypes …
last 15 years. Given their plasticity, defined as the ability to develop into different phenotypes …
[HTML][HTML] Intranasally administered mesenchymal stem cells promote a regenerative niche for repair of neonatal ischemic brain injury
V Donega, CH Nijboer, G van Tilborg… - Experimental …, 2014 - Elsevier
Previous work from our group has shown that intranasal MSC-treatment decreases lesion
volume and improves motor and cognitive behavior after hypoxic–ischemic (HI) brain …
volume and improves motor and cognitive behavior after hypoxic–ischemic (HI) brain …