Impact of diabetes in patients diagnosed with COVID-19

M Abu-Farha, F Al-Mulla, TA Thanaraj… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a disease caused by the coronavirus SARS-CoV-2 (Severe Acute Respiratory
Syndrome Coronavirus-2), known as a highly contagious disease, currently affecting more …

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) has posed a significant threat to global health. This …

In silico drug discovery of major metabolites from spices as SARS-CoV-2 main protease inhibitors

MAA Ibrahim, AHM Abdelrahman, TA Hussien… - Computers in Biology …, 2020 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) is an infectious illness caused by Severe
Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), originally identified in Wuhan …

Comprehensive characterization of N-and O-glycosylation of SARS-CoV-2 human receptor angiotensin converting enzyme 2

A Shajahan, S Archer-Hartmann, NT Supekar… - …, 2021 - academic.oup.com
The emergence of the coronavirus disease 2019 (COVID-19) pandemic caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created the need for …

ACE2 in the era of SARS-CoV-2: controversies and novel perspectives

F Saponaro, G Rutigliano, S Sestito… - Frontiers in Molecular …, 2020 - frontiersin.org
Angiotensin-converting enzyme 2 (ACE2) is related to ACE but turned out to counteract
several pathophysiological actions of ACE. ACE2 exerts antihypertensive and …

A review on possible mechanistic insights of Nitazoxanide for repurposing in COVID-19

AS Lokhande, PV Devarajan - European Journal of Pharmacology, 2021 - Elsevier
The global pandemic of Coronavirus Disease 2019 (COVID-19) has brought the world to a
grinding halt. A major cause of concern is the respiratory distress associated mortality …

Impact of COVID-19 on the cardiovascular system: a review of available reports

RS Soumya, TG Unni, KG Raghu - Cardiovascular drugs and therapy, 2021 - Springer
The recent emergence of the coronavirus disease 19 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) in China is now a global health …

[HTML][HTML] Endothelial glycocalyx damage as a systemic inflammatory microvascular endotheliopathy in COVID-19

M Yamaoka-Tojo - Biomedical journal, 2020 - Elsevier
In atherosclerosis patients, vascular endothelial dysfunction is commonly observed
alongside damage of the vascular endothelial glycocalyx, an extracellular matrix bound to …

Obesity and diabetes as comorbidities for COVID-19: Underlying mechanisms and the role of viral–bacterial interactions

IL Kruglikov, M Shah, PE Scherer - Elife, 2020 - elifesciences.org
Obesity and diabetes are established comorbidities for COVID-19. Adipose tissue
demonstrates high expression of ACE2 which SARS-CoV-2 exploits to enter host cells. This …

SARS-CoV-2 infection boosts MX1 antiviral effector in COVID-19 patients

J Bizzotto, P Sanchis, M Abbate, S Lage-Vickers… - Iscience, 2020 - cell.com
In a published case-control study (GSE152075) from SARS-CoV-2-positive (n= 403) and-
negative patients (n= 50), we analyzed the response to infection assessing gene expression …