Benzodiazepines (BZDs) are among one of the most widely prescribed drug classes in the
United States. BZDs are a class of psychoactive drugs known for their depressant effect on …

Importance Primary care clinicians find managing chronic pain challenging. Evidence of
long-term efficacy of opioids for chronic pain is limited. Opioid use is associated with serious …

This guideline provides recommendations for clinicians providing pain care, including those
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …

Background: In response to adverse outcomes from prescription opioids, the Centers for
Disease Control and Prevention (CDC) released the Guideline for Prescribing Opioids for …

Background Prescription opioid use is highly associated with risk of opioid-related death,
with 1 of every 550 chronic opioid users dying within approximately 2.5 years of their first …

Overdose deaths are often viewed as the leading edge of the opioid epidemic which has
gripped the United States over the past two decades (Skolnick, 2018a). This emphasis is …

Objectives To identify trends in concurrent use of a benzodiazepine and an opioid and to
identify the impact of these trends on admissions to hospital and emergency room visits for …

Objective: Goals were to determine the prevalence of benzodiazepine use (as prescribed
and misuse), characterize misuse, and examine variation by age. Methods: A cross …

Objectives. To describe trends in benzodiazepine prescriptions and overdose mortality
involving benzodiazepines among US adults. Methods. We examined data from the Medical …

Abstract The United States opioid epidemic is a nationwide public health crisis. Initially
driven by increased consumption and availability of pharmaceutical opioids, an increasing …