Characteristics, prevention, and management of cardiovascular disease in people living with HIV: a scientific statement from the American Heart Association

MJ Feinstein, PY Hsue, LA Benjamin, GS Bloomfield… - Circulation, 2019 - Am Heart Assoc
As early and effective antiretroviral therapy has become more widespread, HIV has
transitioned from a progressive, fatal disease to a chronic, manageable disease marked by …

Immune and non-immune functions of adipose tissue leukocytes

WV Trim, L Lynch - Nature Reviews Immunology, 2022 - nature.com
Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …

HIV and antiretroviral therapy-related fat alterations

JR Koethe, C Lagathu, JE Lake, P Domingo… - Nature reviews Disease …, 2020 - nature.com
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

Obesity and weight gain in persons with HIV

SS Bailin, CL Gabriel, CN Wanjalla… - Current HIV/AIDS Reports, 2020 - Springer
Abstract Purpose of Review The proportion of overweight and obese persons with HIV
(PWH) has increased since the introduction of antiretroviral therapy (ART). We aim to …

Adipose tissue is a neglected viral reservoir and an inflammatory site during chronic HIV and SIV infection

A Damouche, T Lazure, V Avettand-Fènoël… - PLoS …, 2015 - journals.plos.org
Two of the crucial aspects of human immunodeficiency virus (HIV) infection are (i) viral
persistence in reservoirs (precluding viral eradication) and (ii) chronic inflammation (directly …

Specific biological features of adipose tissue, and their impact on HIV persistence

C Bourgeois, J Gorwood, A Barrail-Tran… - Frontiers in …, 2019 - frontiersin.org
Although white AT can contribute to anti-infectious immune responses, it can also be
targeted and perturbed by pathogens. The AT's immune involvement is primarily due to …

Hypertension and metabolic syndrome in persons with HIV

SK Masenga, F Elijovich, JR Koethe… - Current hypertension …, 2020 - Springer
Abstract Purpose of Review With the advent of highly active antiretroviral therapy (ART), the
life span of persons with HIV (PWH) has been nearly normalized. With aging, prevalence of …

HIV-1 Vpr induces ciTRAN to prevent transcriptional repression of the provirus

V Bhardwaj, A Singh, A Choudhary, R Dalavi… - Science …, 2023 - science.org
The functional consequences of circular RNA (circRNA) expression on HIV-1 replication are
largely unknown. Using a customized protocol involving direct RNA nanopore sequencing …

Basic science and pathogenesis of ageing with HIV: potential mechanisms and biomarkers

C Lagathu, A Cossarizza, V Béréziat, M Nasi, J Capeau… - Aids, 2017 - journals.lww.com
The increased prevalence of age-related comorbidities and mortality is worrisome in ageing
HIV-infected patients. Here, we aim to analyse the different ageing mechanisms with regard …

Collecting lymphatic vessel permeability facilitates adipose tissue inflammation and distribution of antigen to lymph node–homing adipose tissue dendritic cells

EL Kuan, S Ivanov, EA Bridenbaugh… - The Journal of …, 2015 - journals.aai.org
Collecting lymphatic vessels (CLVs), surrounded by fat and endowed with contractile muscle
and valves, transport lymph from tissues after it is absorbed into lymphatic capillaries. CLVs …