Gene therapy holds great potential for treating almost any disease by gene silencing, protein
expression, or gene correction. To efficiently deliver the nucleic acid payload to its target …

In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream
where they circulate until they reach the target tissue. The ligand on the NP surface …

Besides the wide use of engineered nanomaterials (NMs) in technical products, their
applications are not only increasing in biotechnology and biomedicine, but also in the …

Fundamentally, all interactions between the nanoparticle corona complex and the biological
machinery are mediated by physical forces common to all molecular systems. The …

Protein adsorption is considered to be the most important factor of the interaction between
polymeric biomaterials and body fluids or tissues. Water‐mediated hydrophobic and …

What happens to inorganic nanoparticles (NPs), such as plasmonic gold or silver,
superparamagnetic iron oxide, or fluorescent quantum dot NPs after they have been …

It is now well understood that once in contact with biological fluids, nanoscale objects lose
their original identity and acquire a new biological character, referred to as a protein corona …

This Review aims to provide a systematic analysis of the literature regarding ongoing
debates in protein corona research. Our goal is to portray the current understanding of two …

While the blood vessel is seldom the target tissue, almost all nanomedicine will interact with
blood vessels and blood at some point of time along its life cycle in the human body …

Following systemic administration, liposomes are covered by a 'corona'of proteins, and
preserving the surface functionality is challenging. Coating the liposome surface with …