Thematic Review Series: Sphingolipids. Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease—a review

T Ariga, MP McDonald, KY Robert - Journal of lipid research, 2008 - ASBMB
Gangliosides are expressed in the outer leaflet of the plasma membrane of the cells of all
vertebrates and are particularly abundant in the nervous system. Ganglioside metabolism is …

Disease-modifying therapies for Alzheimer disease: challenges to early intervention

JL Cummings, R Doody, C Clark - Neurology, 2007 - AAN Enterprises
Prevention of Alzheimer disease (AD) is a national and global imperative. Therapy is
optimally initiated when individuals are asymptomatic or exhibit mild cognitive impairment …

Bioengineered sequential growth factor delivery stimulates brain tissue regeneration after stroke

Y Wang, MJ Cooke, N Sachewsky… - Journal of Controlled …, 2013 - Elsevier
Stroke is a leading cause of disability with no effective regenerative treatment. One
promising strategy for achieving tissue repair involves the stimulation of endogenous neural …

Protective Effects of a Rhodiola Crenulata Extract and Salidroside on Hippocampal Neurogenesis against Streptozotocin-Induced Neural Injury in the Rat

Z Qu, Y Zhou, Y Zeng, Y Lin, Y Li, Z Zhong, WY Chan - PloS one, 2012 - journals.plos.org
Previously we have demonstrated that a Rhodiola crenulata extract (RCE), containing a
potent antioxidant salidroside, promotes neurogenesis in the hippocampus of depressive …

Nanotechnology solutions for Alzheimer's disease: advances in research tools, diagnostic methods and therapeutic agents

A Nazem, GA Mansoori - Journal of Alzheimer's disease, 2008 - content.iospress.com
A century of research has passed since the discovery and definition of Alzheimer's disease
(AD), the primary common dementing disorder worldwide. However, AD lacks definite …

Interruption of β-catenin signaling reduces neurogenesis in Alzheimer's disease

P He, Y Shen - Journal of Neuroscience, 2009 - Soc Neuroscience
The neuronal loss associated with Alzheimer's disease (AD) affects areas of the brain that
are vital to cognition. Although recent studies have shown that new neurons can be …

Human intracerebroventricular (ICV) injection of autologous, non-engineered, adipose-derived stromal vascular fraction (ADSVF) for neurodegenerative disorders …

C Duma, O Kopyov, A Kopyov, M Berman… - Molecular Biology …, 2019 - Springer
We have chosen to test the safety of human intracerebroventricular (ICV) brain injections of
autologous non-genetically-modified adipose-derived stromal vascular fraction (ADSVF). In …

Valproic acid as a promising agent to combat Alzheimer's disease

XZ Zhang, XJ Li, HY Zhang - Brain research bulletin, 2010 - Elsevier
Alzheimer's disease (AD) is one of the most threatening diseases to the elderly population at
present. However, there is no yet efficient therapeutic method to AD. Recently, accumulating …

An Overview of Protocols for the Neural Induction of Dental and Oral Stem Cells In Vitro

BC Heng, LW Lim, W Wu, C Zhang - Tissue Engineering Part B …, 2016 - liebertpub.com
To date, various adult stem cells have been identified within the oral cavity, including dental
pulp stem cells, dental follicle stem cells, stem cells from apical papilla, stem cells from …

ABC transporters, neural stem cells and neurogenesis–a different perspective

T Lin, O Islam, K Heese - Cell research, 2006 - nature.com
Stem cells intrigue. They have the ability to divide exponentially, recreate the stem cell
compartment, as well as create differentiated cells to generate tissues. Therefore, they …