The role of resveratrol in cancer therapy

JH Ko, G Sethi, JY Um, MK Shanmugam… - International journal of …, 2017 - mdpi.com
Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …

Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action

S Patra, B Pradhan, R Nayak, C Behera, S Das… - Phytomedicine, 2021 - Elsevier
Background Epidemiological studies has revealed that a diet rich in fruits and vegetables
could lower the risk of certain cancers. In this setting, natural polyphenols are potent …

Anticancer molecular mechanisms of resveratrol

EM Varoni, AF Lo Faro, J Sharifi-Rad, M Iriti - Frontiers in nutrition, 2016 - frontiersin.org
Resveratrol is a pleiotropic phytochemical belonging to the stilbene family. Though it is only
significantly present in grape products, a huge amount of preclinical studies investigated its …

Targeting drug chemo-resistance in cancer using natural products

WH Talib, AR Alsayed, M Barakat, MI Abu-Taha… - Biomedicines, 2021 - mdpi.com
Cancer is one of the leading causes of death globally. The development of drug resistance
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …

Resveratrol and clinical trials: the crossroad from in vitro studies to human evidence

J Tomé-Carneiro, M Larrosa… - Current …, 2013 - benthamdirect.com
Resveratrol (3, 5, 4'-trihydroxy-trans-stilbene) is a non-flavonoid polyphenol that may be
present in a limited number of foodstuffs such as grapes and red wine. Resveratrol has been …

Chemotherapeutic efficacy of curcumin and resveratrol against cancer: Chemoprevention, chemoprotection, drug synergism and clinical pharmacokinetics

S Patra, B Pradhan, R Nayak, C Behera, L Rout… - Seminars in cancer …, 2021 - Elsevier
The frequent inefficiency of conventional cancer therapies due to drug resistance, non-
targeted drug delivery, chemotherapy-associated toxic side effects turned the focus to …

Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer

N Hasima, B Ozpolat - Cell death & disease, 2014 - nature.com
Autophagy, a lysosomal degradation pathway for cellular constituents and organelles, is an
adaptive and essential process required for cellular homeostasis. Although autophagy …

Botany, phytochemistry, pharmacology, and potential application of Polygonum cuspidatum Sieb. et Zucc.: a review

W Peng, R Qin, X Li, H Zhou - Journal of ethnopharmacology, 2013 - Elsevier
Abstract Ethnopharmacological relevance Polygonum cuspidatum Sieb. et Zucc.(Polygonum
cuspidatum), also known as Reynoutria japonica Houtt and Huzhang in China, is a …

New visions on natural products and cancer therapy: autophagy and related regulatory pathways

A Martelli, M Omrani, M Zarghooni, V Citi, S Brogi… - Cancers, 2022 - mdpi.com
Simple Summary In the past few years, clinical as well as regular scientists have been
paying attention to medicinal applications of natural products. There are several …

Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells

H Miki, N Uehara, A Kimura… - International …, 2012 - spandidos-publications.com
Abstract Resveratrol (Res; 3, 4', 5-trihydroxy-trans-stilbene), which is a polyphenol found in
grapes, can block cell proliferation and induce growth arrest and/or cell death in several …