Secretome of Intestinal Bacilli: A Natural Guard against Pathologies

ON Ilinskaya, VV Ulyanova, DR Yarullina… - Frontiers in …, 2017 - frontiersin.org
Current studies of human gut microbiome usually do not consider the special functional role
of transient microbiota, although some of its members remain in the host for a long time and …

The CD8+ T Cell Noncytotoxic Antiviral Responses

MG Morvan, FC Teque, CP Locher… - … and Molecular Biology …, 2021 - Am Soc Microbiol
The CD8+ T cell noncytotoxic antiviral response (CNAR) was discovered during studies of
asymptomatic HIV-infected subjects more than 30 years ago. In contrast to CD8+ T cell …

Biological activities of secretory RNases: Focus on their oligomerization to design antitumor drugs

G Gotte, M Menegazzi - Frontiers in Immunology, 2019 - frontiersin.org
Ribonucleases (RNases) are a large number of enzymes gathered into different bacterial or
eukaryotic superfamilies. Bovine pancreatic RNase A, bovine seminal BS-RNase, human …

Host defence RNases as antiviral agents against enveloped single stranded RNA viruses

J Li, E Boix - Virulence, 2021 - Taylor & Francis
Owing to the recent outbreak of Coronavirus Disease of 2019 (COVID-19), it is urgent to
develop effective and safe drugs to treat the present pandemic and prevent other viral …

Opuntin B, the antiviral protein isolated from prickly pear (Opuntia ficus-indica (L.) Miller) cladode exhibits ribonuclease activity

R Rasoulpour, K Izadpanah, A Afsharifar - Microbial pathogenesis, 2020 - Elsevier
An antiviral protein, designated Opuntin B, was purified from Prickly Pear (Opuntia ficus-
indica (L.) Miller) Cladode by heat treatment of the extract, protein precipitation by …

Bacterial ribonuclease binase exerts an intra-cellular anti-viral mode of action targeting viral RNAs in influenza a virus-infected MDCK-II cells

R Shah Mahmud, A Mostafa, C Müller, P Kanrai… - Virology journal, 2018 - Springer
Background Influenza is a severe contagious disease especially in children, elderly and
immunocompromised patients. Beside vaccination, the discovery of new anti-viral agents …

Evaluation on the antiviral activity of Bacillus velezensis extract against spring viremia of carp virus

K Song, F Luo, W Chen, X Qi, Y Shen, J Zha, F Ling… - Aquaculture, 2022 - Elsevier
Spring viremia of carp virus (SVCV), a member of the family Rhabdoviridae, can cause acute
haemorrhagic and contagious viraemia in cyprinids. In this study, the ethyl acetate extract …

Nuclease-like metalloscissors: Biomimetic candidates for cancer and bacterial and viral infections therapy

M Anjomshoa, B Amirheidari - Coordination Chemistry Reviews, 2022 - Elsevier
Despite the extensive and rapid discovery of modern drugs for treatment of cancer, microbial
infections, and viral illnesses; these diseases are still among major global health concerns …

Anti-influenza activity of the ribonuclease binase: Cellular targets detected by quantitative proteomics

V Ulyanova, R Shah Mahmud, A Laikov… - International Journal of …, 2020 - mdpi.com
Unpredictable influenza pandemics, annual epidemics, and sporadic poultry-to-human
avian influenza virus infections with high morbidity and mortality rates dictate a need to …

An unintentional discovery of a fluorogenic DNA probe for ribonuclease I

D Chang, T Chang, B Salena, Y Li - ChemBioChem, 2020 - Wiley Online Library
Ribonuclease I belongs to a class of nonspecific endoribonucleases and plays many
important roles in a variety of biological and cellular processes. While their ubiquitous nature …