A review on traditionally used South African medicinal plants, their secondary metabolites and their potential development into anticancer agents

D Twilley, S Rademan, N Lall - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Approximately 70% of anticancer drugs were developed
or derived from natural products or plants. Southern Africa boasts an enormous floral …

The antibacterial activity of extracts of nine plant species with good activity against Escherichia coli against five other bacteria and cytotoxicity of extracts

IL Elisha, FS Botha, LJ McGaw, JN Eloff - BMC complementary and …, 2017 - Springer
Background The development of antibiotic resistant bacteria stems from a number of factors,
including inappropriate use of antibiotics in human and animal health and their prolonged …

The anti-arthritic, anti-inflammatory, antioxidant activity and relationships with total phenolics and total flavonoids of nine South African plants used traditionally to treat …

IL Elisha, JP Dzoyem, LJ McGaw, FS Botha… - BMC complementary and …, 2016 - Springer
Background Oxidative stress predisposes the human and animal body to diseases like
cancer, diabetes, arthritis, rheumatoid arthritis, atherosclerosis and chronic inflammatory …

Bioprospecting of South African plants as a unique resource for bioactive endophytic microbes

MA Abdalla, LJ McGaw - Frontiers in pharmacology, 2018 - frontiersin.org
South Africa has a long history and strong belief in traditional herbal medicines. Using
ethnobotanical knowledge as a lead, a large number of South African medicinal plants have …

[HTML][HTML] Acute and sub-chronic toxicities assessment of methanol bark extract of Hypericum roeperianum in rats

MGF Guefack, F Damen, CMN Ngaffo… - South African Journal of …, 2022 - Elsevier
The methanolic crude extract of Hypericum roeperianum bark has previously demonstrated
interesting cytotoxic properties on panels of human and animal cancer cell lines, involving …

Potency and selectivity indices of acetone leaf extracts of nine selected South African trees against six opportunistic Enterobacteriaceae isolates from commercial …

IL Elisha, AR Jambalang, FS Botha, EM Buys… - … and alternative medicine, 2017 - Springer
Background The rise in antimicrobial resistance in a plethora of nosocomial and
opportunistic bacterial pathogens often isolated from commercial eggs, poses a serious …

Traditional medicinal uses, phytochemistry, bioactivities and toxicity of the Genus Maesa (Primulaceae): A comprehensive review

A Barman, M Barman, R Das, S Ray - Journal of Herbal Medicine, 2023 - Elsevier
Abstract Introduction The genus Maesa, belonging to the Primulaceae family, comprises
approximately 150 species that are widely distributed in Western Asia, New Guinea …

A review of ethnoveterinary knowledge, biological activities and secondary metabolites of medicinal woody plants used for managing animal health in South Africa

KM Selogatwe, JA Asong, M Struwig, RV Ndou… - Veterinary …, 2021 - mdpi.com
Globally, the use of ethnoveterinary medicine as remedies for animal health among different
ethnic groups justify the need for a systematic exploration to enhance their potential. In …

Suppressive, Curative, and Prophylactic Effects of Maesa lanceolata Forssk. against Rodent Malaria Parasite Plasmodium berghei

E Tekalign, G Tadege, N Fisseha… - BioMed Research …, 2022 - Wiley Online Library
The artemisinin partial resistance is believed to be spread to artemisinin‐based combination
therapy partner drugs. As a result, new antiplasmodial compounds are required to treat …

Pittosporum viridiflorum Sims (Pittosporaceae): A review on a useful medicinal plant native to South Africa and tropical Africa

B Madikizela, LJ McGaw - Journal of Ethnopharmacology, 2017 - Elsevier
Abstract Ethnopharmacological relevance Pittosporum viridiflorum Sims, a Pittosporaceae
species, is used extensively in African traditional medicine (ATM) by various tribes. This …