Structure and function of type II DNA topoisomerases.
PM Watt, ID Hickson - Biochemical Journal, 1994 - ncbi.nlm.nih.gov
INTRODUCTION The faithful replication and segregation of chromosomes as part of the cell
division cycle requires that topological changes be imposed upon cellular DNA …
division cycle requires that topological changes be imposed upon cellular DNA …
Mechanical determinants of chromatin topology and gene expression
The compaction of linear DNA into micrometer-sized nuclear boundaries involves the
establishment of specific three-dimensional (3D) DNA structures complexed with histone …
establishment of specific three-dimensional (3D) DNA structures complexed with histone …
[HTML][HTML] ATP-dependent positive supercoiling of DNA by 13S condensin: a biochemical implication for chromosome condensation
K Kimura, T Hirano - Cell, 1997 - cell.com
Abstract 13S condensin is a five-subunit protein complex that plays a central role in mitotic
chromosome condensation in Xenopus egg extracts. Two core subunits of this complex …
chromosome condensation in Xenopus egg extracts. Two core subunits of this complex …
The functional response of upstream DNA to dynamic supercoiling in vivo
F Kouzine, S Sanford, Z Elisha-Feil… - Nature structural & …, 2008 - nature.com
Because RNA polymerase is a powerful motor, transmission of transcription-generated
forces might directly alter DNA structure, chromatin or gene activity in mammalian cells. Here …
forces might directly alter DNA structure, chromatin or gene activity in mammalian cells. Here …
Occurrence of potential cruciform and H-DNA forming sequences in genomic DNA
GP Schroth, PS Ho - Nucleic acids research, 1995 - academic.oup.com
We have used computer-assisted methods to search large amounts of the human, yeast and
Escherichla coll genomes for inverted repeat (IR) and mirror repeat (MR) DNA sequence …
Escherichla coll genomes for inverted repeat (IR) and mirror repeat (MR) DNA sequence …
Single-molecule visualization of twin-supercoiled domains generated during transcription
R Janissen, R Barth, M Polinder… - Nucleic Acids …, 2024 - academic.oup.com
Transcription-coupled supercoiling of DNA is a key factor in chromosome compaction and
the regulation of genetic processes in all domains of life. It has become common knowledge …
the regulation of genetic processes in all domains of life. It has become common knowledge …
The importance of being supercoiled: how DNA mechanics regulate dynamic processes
L Baranello, D Levens, A Gupta, F Kouzine - Biochimica et Biophysica Acta …, 2012 - Elsevier
Through dynamic changes in structure resulting from DNA–protein interactions and
constraints given by the structural features of the double helix, chromatin accommodates …
constraints given by the structural features of the double helix, chromatin accommodates …
The ubiquitous chromatin protein DEK alters the structure of DNA by introducing positive supercoils
T Waldmann, C Eckerich, M Baack, C Gruss - Journal of Biological …, 2002 - ASBMB
We have investigated the molecular mechanism by which the proto-oncogene protein DEK,
an abundant chromatin-associated protein, changes the topology of DNA in chromatin in …
an abundant chromatin-associated protein, changes the topology of DNA in chromatin in …
Type III restriction endonucleases translocate DNA in a reaction driven by recognition site‐specific ATP hydrolysis.
A Meisel, P Mackeldanz, TA Bickle, DH Krüger… - The EMBO …, 1995 - embopress.org
Type III restriction/modification systems recognize short non‐palindromic sequences, only
one strand of which can be methylated. Replication of type III‐modified DNA produces …
one strand of which can be methylated. Replication of type III‐modified DNA produces …