A review on the biomedical efficacy of transition metal triazole compounds
From the apocalyptic era of antibiotic resistance, the scientific community around the world is
engaged in designing and developing metal-based compounds to inhibit and control …
engaged in designing and developing metal-based compounds to inhibit and control …
Schiff base metallodrugs in antimicrobial and anticancer chemotherapy applications: a comprehensive review
The proliferation in cancer and multidrug-resistant infections amidst personage with the
evolution of civilization is an alarming bone of contention. Cancer has long been the pre …
evolution of civilization is an alarming bone of contention. Cancer has long been the pre …
Synthesis, structural, molecular docking and spectroscopic studies of (E)-N'-(4-methoxybenzylidene)-5-methyl-1H-pyrazole-3-carbohydrazide
Abstract (E)-N'-4-methoxybenzylidene-5-methyl-1H-pyrazole-3-carbohydrazide (E-MBPC)
has been synthesized and characterized by FT-IR, 1 H & 13 C NMR and ESI-MS …
has been synthesized and characterized by FT-IR, 1 H & 13 C NMR and ESI-MS …
Synthesis, biological activity and POM/DFT/docking analyses of annulated pyrano [2, 3-d] pyrimidine derivatives: Identification of antibacterial and antitumor …
Abstract New annulated pyrano [2, 3-d] pyrimidine derivatives were synthesized with
hydroxyl, methoxy, bromine, nitrile and nitro substituents on its skeleton. The correlated …
hydroxyl, methoxy, bromine, nitrile and nitro substituents on its skeleton. The correlated …
In vitro potential antiviral SARS-CoV-19-activity of natural product thymohydroquinone and dithymoquinone from Nigella sativa
ER Esharkawy, F Almalki, TB Hadda - Bioorganic Chemistry, 2022 - Elsevier
Inflammation, oxidation, and compromised immunity all increase the dangers of COVID-19,
whereas many pharmaceutical protocols may lead to increased immunity such as ingesting …
whereas many pharmaceutical protocols may lead to increased immunity such as ingesting …
Synthesis, characterization, and in vitro antibacterial activity of some new pyridinone and pyrazole derivatives with some in silico ADME and molecular modeling study
KE Saadon, NMH Taha, NA Mahmoud… - Journal of the Iranian …, 2022 - Springer
A new series of pyridine-2-one and pyrazole derivatives were designed and synthesized
based on cyanoacrylamide derivatives containing 2, 4-dichlro aniline and 6-methyl 2-amino …
based on cyanoacrylamide derivatives containing 2, 4-dichlro aniline and 6-methyl 2-amino …
Crystallographic study, biological assessment and POM/Docking studies of pyrazoles-sulfonamide hybrids (PSH): Identification of a combined Antibacterial/Antiviral …
M Chalkha, A Nakkabi, TB Hadda, M Berredjem… - Journal of Molecular …, 2022 - Elsevier
The discovery and development of new potent antimicrobial and antioxidant agents is an
essential lever to protect living beings against pathogenic microorganisms and free radicals …
essential lever to protect living beings against pathogenic microorganisms and free radicals …
How to face COVID-19: proposed treatments based on remdesivir and hydroxychloroquine in the presence of zinc sulfate. Docking/DFT/POM structural analysis
T Ben Hadda, M Berredjem, FA Almalki… - Journal of …, 2022 - Taylor & Francis
Remdesivir and hydroxychloroquine derivatives form two important classes of heterocyclic
compounds. They are known for their anti-malarial biological activity. This research aims to …
compounds. They are known for their anti-malarial biological activity. This research aims to …
[HTML][HTML] In vitro and in silico evaluation of the antimicrobial and antioxidant activities of spiropyrazoline oxindole congeners
M Chalkha, K Chebbac, H Nour, A Nakkabi… - Arabian Journal of …, 2024 - Elsevier
The search for novel powerful antimicrobial and antioxidant agents is considered a dynamic
field in medicinal chemistry. In this context, a series of spiropyrazoline indolin-3-one …
field in medicinal chemistry. In this context, a series of spiropyrazoline indolin-3-one …
Synthesis, structural, biocomputational modeling and antifungal activity of novel armed pyrazoles
Nowadays, facile and short synthesis of new antifungal pyrazole-derivatives ligands has
attracted increasing attention due to their simplicity and effectiveness. In here, we have …
attracted increasing attention due to their simplicity and effectiveness. In here, we have …