The HIV reservoir in monocytes and macrophages

ME Wong, A Jaworowski, AC Hearps - Frontiers in immunology, 2019 - frontiersin.org
In people living with HIV (PLWH) who are failing or unable to access combination
antiretroviral therapy (cART), monocytes and macrophages are important drivers of …

The role of the ATP-binding cassette A1 (ABCA1) in human disease

L Jacobo-Albavera, M Domínguez-Pérez… - International journal of …, 2021 - mdpi.com
Cholesterol homeostasis is essential in normal physiology of all cells. One of several
proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 …

Declined serum high density lipoprotein cholesterol is associated with the severity of COVID-19 infection

X Hu, D Chen, L Wu, G He, W Ye - Clinica Chimica Acta, 2020 - Elsevier
Background COVID-19 infection is epidemic worldwide. We describe the serum lipid profile
of the patients with COVID-19 infection. Methods In this retrospective study, we collected the …

Are reactive oxygen species always detrimental to pathogens?

CN Paiva, MT Bozza - Antioxidants & redox signaling, 2014 - liebertpub.com
Reactive oxygen species (ROS) are deadly weapons used by phagocytes and other cell
types, such as lung epithelial cells, against pathogens. ROS can kill pathogens directly by …

Infections, atherosclerosis, and coronary heart disease

NVK Pothineni, S Subramany, K Kuriakose… - European heart …, 2017 - academic.oup.com
Atherosclerosis is a chronic inflammatory disease. Pathophysiological similarities between
chronic infections and atherosclerosis triggered interest in a clinical association between …

Modulation of macrophage immunometabolism: A new approach to fight infections

T Gauthier, W Chen - Frontiers in Immunology, 2022 - frontiersin.org
Macrophages are essential innate immune cells that contribute to host defense during
infection. An important feature of macrophages is their ability to respond to extracellular cues …

[图书][B] Introduction to syndemics: A critical systems approach to public and community health

M Singer - 2009 - books.google.com
This book explains the growing field of syndemic theory and research, a framework for the
analysis and prevention of disease interactions that addresses underlying social and …

Cholesterol and triglyceride concentrations, COVID-19 severity, and mortality: a systematic review and meta-analysis with meta-regression

A Zinellu, P Paliogiannis, AG Fois, P Solidoro… - Frontiers in public …, 2021 - frontiersin.org
Lipid profile alterations have been observed in patients with coronavirus disease 2019
(COVID-19) in relation to disease severity and mortality. We conducted a systematic review …

Pathogens and atherosclerosis: update on the potential contribution of multiple infectious organisms to the pathogenesis of atherosclerosis

ME Rosenfeld, LA Campbell - Thrombosis and haemostasis, 2011 - thieme-connect.com
It is currently unclear what causes the chronic inflammation within atherosclerotic plaques.
One emerging paradigm suggests that infection with bacteria and/or viruses can contribute …

HIV Nef is Secreted in Exosomes and Triggers Apoptosis in Bystander CD4+ T Cells

M Lenassi, G Cagney, M Liao, T Vaupotič… - Traffic, 2010 - Wiley Online Library
The HIV accessory protein negative factor (Nef) is one of the earliest and most abundantly
expressed viral proteins. It is also found in the serum of infected individuals (Caby MP …