Redox dysregulation as a driver for DNA damage and its relationship to neurodegenerative diseases

S Shadfar, S Parakh, MS Jamali, JD Atkin - Translational …, 2023 - Springer
Redox homeostasis refers to the balance between the production of reactive oxygen species
(ROS) as well as reactive nitrogen species (RNS), and their elimination by antioxidants. It is …

ERp57/PDIA3: new insight

S Chichiarelli, F Altieri, G Paglia, E Rubini… - Cellular & Molecular …, 2022 - Springer
The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and, although
predominantly located in the endoplasmic reticulum (ER), has indeed been found in other …

Transcriptome analysis provides insights into hepatic responses to moderate heat stress in the rainbow trout (Oncorhynchus mykiss)

Y Li, J Huang, Z Liu, Y Zhou, B Xia, Y Wang, Y Kang… - Gene, 2017 - Elsevier
The rainbow trout is an economically important fish in the world. The limited stress tolerance
of this species to high summer-like temperatures usually leads to mass mortality and great …

Alterations to transcriptomic profile, histopathology, and oxidative stress in liver of pikeperch (Sander lucioperca) under heat stress

Y Wang, C Li, C Pan, E Liu, X Zhao, Q Ling - Fish & shellfish immunology, 2019 - Elsevier
Pikeperch (Sander lucioperca) is an economically important cool-water fish. In recent years,
its cultivation has become threatened by higher temperatures in summer. We previously …

ERp57/GRP58: a protein with multiple functions

C Turano, E Gaucci, C Grillo… - Cellular and Molecular …, 2011 - degruyter.com
The protein ERp57/GRP58 is a stress-responsive protein and a component of the protein
disulfide isomerase family. Its functions in the endoplasmic reticulum are well known …

Multifunctional molecule ERp57: From cancer to neurodegenerative diseases

A Hettinghouse, R Liu, C Liu - Pharmacology & therapeutics, 2018 - Elsevier
The protein disulfide isomerase (PDI) gene family is a protein family classically
characterized by endoplasmic reticulum (ER) localization and isomerase and redox activity …

Nonylphenol induces apoptosis in rat testicular Sertoli cells via endoplasmic reticulum stress

Y Gong, J Wu, Y Huang, S Shen, X Han - Toxicology letters, 2009 - Elsevier
Nonylphenol (NP) is a widely distributed environment contaminant and has been
documented to disrupt testicular development and decrease male fertility. Amongst possible …

[PDF][PDF] PDIA3 and PDIA6 gene expression as an aggressiveness marker in primary ductal breast cancer

FS Ramos, LT Serino, CM Carvalho, RS Lima… - Genet Mol …, 2015 - funpecrp.com.br
Changes in the expression of the protein disulfide isomerase genes PDIA3and PDIA6may
increase endoplasmic reticulum stress, leading to cellular instability and neoplasia. We …

Protein Disulfide Isomerase A3 (PDIA3): A Pharmacological Target in Glioblastoma?

G Paglia, M Minacori, G Meschiari, S Fiorini… - International Journal of …, 2023 - mdpi.com
The protein disulfide isomerase A3 (PDIA3) is directly or indirectly involved in various
physiopathological processes and participates in cancer initiation, progression and …

Insights into role of bromodomain, testis-specific (Brdt) in acetylated histone H4-dependent chromatin remodeling in mammalian spermiogenesis

S Dhar, A Thota, MRS Rao - Journal of Biological Chemistry, 2012 - ASBMB
Mammalian spermiogenesis is of considerable biological interest especially due to the
unique chromatin remodeling events that take place during spermatid maturation. Here, we …