Autosomal dominant non-syndromic hearing loss (HL) typically occurs when only one
dominant allele within the disease gene is sufficient to express the phenotype. Therefore …

Vaccination against measles, mumps, and rubella (MMR) and yellow fever (YF) with live
attenuated viruses can rarely cause life-threatening disease. Severe illness by MMR …

Type I IFNs, a family of cytokines that signal through a single receptor and signaling
mechanism, were originally named for their ability to interfere with viral replication. While …

Over the past decade, advancements in high-throughput sequencing have greatly enhanced
our knowledge of the mutational signatures responsible for hereditary hearing loss. In its …

Genetic hearing loss crosses almost all the categories of hearing loss which includes the
following: conductive, sensory, and neural; syndromic and nonsyndromic; congenital …

Literature and clinical practice around adult‐onset hearing loss (HL) has traditionally
focused on environmental risk factors, including noise exposure, ototoxic drug exposure …

The fimbrin protein family contains a variety of proteins, among which Plastin1 (PLS1) is an
important member. According to recent studies, variations in the coding region of the PLS1 …

Hereditary hearing loss is one of the most common sensory disabilities worldwide. Mutation
of POU domain class 4 transcription factor 3 (POU4F3) is considered the pathogenic cause …

Sensorineural hearing loss, the most common form of hearing impairment, is mainly
attributable to genetic mutations or acquired factors, such as aging, noise exposure, and …

Hearing loss (HL) is one of the most common disabilities in the world. In industrialized
countries, HL occurs in 1–2/1,000 newborns, and approximately 60% of HL is caused by …