Platelets are a major player and represent a therapeutic opportunity in systemic lupus erythematosus

M Robert, M Scherlinger - Joint Bone Spine, 2024 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by immune
dysregulation and organ injury with a premature mortality due to cardiovascular diseases …

[HTML][HTML] Gout incidence and management during the COVID-19 pandemic in England, UK: a nationwide observational study using OpenSAFELY

MD Russell, J Massey, E Roddy… - The Lancet …, 2023 - thelancet.com
Background Gout is the most prevalent inflammatory arthritis, yet one of the worst managed.
Our objective was to assess how the COVID-19 pandemic impacted incidence and quality of …

Barriers to the diagnosis of early inflammatory arthritis: a literature review

L Saraiva, C Duarte - Open Access Rheumatology: Research and …, 2023 - Taylor & Francis
The early identification of patients with inflammatory arthritis and their referral to
rheumatologists in order to establish a diagnosis and to start treatment plays a crucial role in …

OpenSAFELY: The impact of COVID‐19 on azathioprine, leflunomide and methotrexate monitoring, and factors associated with change in monitoring rate

AD Brown, L Fisher, HJ Curtis… - British Journal of …, 2024 - Wiley Online Library
Aims The COVID‐19 pandemic created unprecedented pressure on healthcare services.
This study investigates whether disease‐modifying antirheumatic drug (DMARD) safety …

The protocol of a clinical effectiveness trial comparing standard step-up care, early combination DMARD therapy and early use of TNF inhibitors for the treatment of …

M Watson, W Tillett, D Jadon… - Therapeutic …, 2024 - journals.sagepub.com
Objectives: The aim of the Severe Psoriatic arthritis–Early intervEntion to control Disease
trial is to compare outcomes in psoriatic arthritis (PsA) patients with poor prognostic factors …

[HTML][HTML] The safety of antivirals and neutralising monoclonal antibodies used in prehospital treatment of Covid-19

K Bechman, ACA Green, MD Russell, Z Yang… - Journal of Infection, 2024 - Elsevier
Objective This proof-of-principle pharmacovigilance study used Electronic Health Record
(EHR) data to examine the safety of sotrovimab, paxlovid and molnupiravir in prehospital …

Incidence of clinically diagnosed psoriatic arthritis in Sweden

S Exarchou, D Di Giuseppe, E Klingberg… - The Journal of …, 2024 - jrheum.org
Objective Prior incidence estimates of psoriatic arthritis (PsA) vary considerably. We aimed
to assess the annual incidence of clinically diagnosed PsA among adults in Sweden 2014 …

[HTML][HTML] Trends in Gout Incidence and Management during the COVID-19 Pandemic: A Nationwide Study in England via OpenSAFELY

MD Russell, J Massey, E Roddy… - The Lancet …, 2023 - ncbi.nlm.nih.gov
Background Gout is the most prevalent inflammatory arthritis, yet one of the worst managed.
Our objective was to assess how the COVID-19 pandemic impacted on incidence and care …

[HTML][HTML] Disease-Modifying Medications in Patients with Rheumatoid Arthritis in the USA: Trends from 2016 to 2021

SK Peasah, ECS Swart, Y Huang, SL Kane-Gill… - Drugs-Real World …, 2024 - Springer
Background Disease-modifying anti-rheumatic drugs (DMARDs), since their introduction in
1990, have revolutionized the management of rheumatoid arthritis. Newer DMARDs have …

Trust performance in managing inflammatory arthritis over time in England and Wales: a latent class analysis approach

Z Yang, N Arumalla, E Alveyn… - … Advances in Practice, 2024 - academic.oup.com
Objectives To evaluate trust-level performance in time to initiation of DMARD therapy in
patients with early inflammatory arthritis (EIA), with identification of the change in …