Metabolic control by AMPK in white adipose tissue

O Göransson, F Kopietz, MH Rider - Trends in Endocrinology & Metabolism, 2023 - cell.com
White adipose tissue (WAT) plays an important role in the integration of whole-body
metabolism by storing fat and mobilizing triacylglycerol when needed. The released free …

The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions

S Alshehade, MA Alshawsh, V Murugaiyah, M Asif… - Life sciences, 2022 - Elsevier
Metabolic dysfunction-associated fatty liver disease (MAFLD), proposed in 2020 is a novel
term for non-alcoholic fatty liver disease (NAFLD) which was coined for the first time in 1980 …

[HTML][HTML] The effects of the tumor suppressor gene PTEN on the proliferation and apoptosis of breast cancer cells via AKT phosphorylation

J Zhang, Y Zhang, X Lin, X Han… - Translational Cancer …, 2023 - ncbi.nlm.nih.gov
Background The proliferation and apoptosis of cancer cells play important roles in breast
carcinomas. However, to date, there have been few reports on the correlation between the …

[HTML][HTML] Mechanism of Gegen Qinlian Decoction regulating ABTB1 expression in colorectal cancer metastasis based on PI3K/AKT/FOXO1 pathway

F Li, L Chen, J Zheng, J Yang, X Song… - BioMed Research …, 2022 - ncbi.nlm.nih.gov
It was to investigate the role of Gegen Qinlian decoction (GQD) in the regulation of ABTB1
gene based on PI3K/AKT/FOXO1 signaling pathway in colorectal cancer (CRC) metastasis …

AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue

SJ Chuang, M Johanns, S Pyr dit Ruys… - Biochemical …, 2021 - portlandpress.com
The effects of small-molecule AMP-activated protein kinase (AMPK) activators in rat
epididymal adipocytes were compared. SC4 was the most effective and submaximal doses …

Insulin activates LC-PUFA biosynthesis of hepatocytes by regulating the PI3K/Akt/mTOR/Srebp1 pathway in teleost Siganus canaliculatus

L Liu, C Chen, Y Dong, Y Cheng, C You… - … and Physiology Part B …, 2022 - Elsevier
Insulin is well known an important metabolic regulator in glucose and lipid metabolism. It
has been proved to activate long-chain (≥ C 20) polyunsaturated fatty acids (LC-PUFA) …

[PDF][PDF] AMP-activated protein kinase in adipose tissue

F Kopietz - 2021 - portal.research.lu.se
AMP-activated protein kinase in adipose tissue Kopietz, Franziska Page 1 AMP-activated
protein kinase in adipose tissue Kopietz, Franziska 2021 Document Version: Publisher's PDF …