Novel insights from basic and translational studies are reshaping concepts of the
immunopathogenesis of multiple sclerosis and understanding of the different inflammatory …

There is growing recognition that B cell contributions to normal immune responses extend
well beyond their potential to become antibody-producing cells, including roles at the innate …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) that is characterised pathologically by demyelination, gliosis, neuro-axonal damage …

Abstract Inhibition of Bruton's Tyrosine Kinase (BTKi) is now viewed as a promising next-
generation B-cell-targeting therapy for autoimmune diseases including multiple sclerosis …

Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other
microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology …

The fungal microbiota (mycobiota) is an integral part of the microbial community colonizing
the body surfaces and is involved in many key aspects of human physiology, while an …

Fungi can cause disease in humans, from mucocutaneous to life-threatening systemic
infections. Initiation of antifungal immunity involves fungal recognition by pattern recognition …

Despite the availability of a lot of effective disease-modifying drugs, multiple sclerosis
(MS)(in particular the progressive forms) still represents an important unmet medical need …

Background and Objectives There has been growing interest in potential roles of the
immune system in the pathogenesis of Parkinson disease (PD). The aim of the current study …

Systemic candidiasis is an invasive fungal infection caused by members of the genus
Candida. The recent emergence of antifungal drug resistance and increased incidences of …