International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems

VS Lin, W Chen, M Xian, CJ Chang - Chemical Society Reviews, 2015 - pubs.rsc.org
Hydrogen sulfide (H2S), a gaseous species produced by both bacteria and higher
eukaryotic organisms, including mammalian vertebrates, has attracted attention in recent …

Hydrogen sulfide (H 2 S) releasing agents: chemistry and biological applications

Y Zhao, TD Biggs, M Xian - Chemical communications, 2014 - pubs.rsc.org
Hydrogen sulfide (H2S) is a newly recognized signaling molecule with very potent
cytoprotective actions. The fields of H2S physiology and pharmacology have been rapidly …

[HTML][HTML] Capture and visualization of hydrogen sulfide via a fluorescent probe

C Liu, J Pan, S Li, Y Zhao, LY Wu… - … (International ed. in …, 2011 - ncbi.nlm.nih.gov
Hydrogen sulfide (H2S) has been known as a toxic pollutant for years. However, this
molecule has been recently recognized as the third gaseous transmitter (the other two are …

[HTML][HTML] Chemical foundations of hydrogen sulfide biology

Q Li, JR Lancaster Jr - Nitric oxide, 2013 - Elsevier
Following nitric oxide (nitrogen monoxide) and carbon monoxide, hydrogen sulfide (or its
newer systematic name sulfane, H 2 S) became the third small molecule that can be both …

Hydrogen sulfide in biochemistry and medicine

BL Predmore, DJ Lefer, G Gojon - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: An abundance of experimental evidence suggests that hydrogen sulfide (H2S)
plays a prominent role in physiology and pathophysiology. Many targets exist for H2S …

Making and working with hydrogen sulfide: the chemistry and generation of hydrogen sulfide in vitro and its measurement in vivo: a review

MN Hughes, MN Centelles, KP Moore - Free Radical Biology and Medicine, 2009 - Elsevier
Hydrogen sulfide is rapidly emerging as an important vasoactive mediator formed in health
and disease. Its biological action is centered on its reactivity with heme-proteins and its …

Cysteine-Activated Hydrogen Sulfide (H2S) Donors

Y Zhao, H Wang, M Xian - Journal of the American Chemical …, 2011 - ACS Publications
H2S, the newly discovered gasotransmitter, plays important roles in biological systems.
However, the research on H2S has been hindered by the lack of controllable H2S donors …

Diallyl Trisulfide Is a Fast H2S Donor, but Diallyl Disulfide Is a Slow One: The Reaction Pathways and Intermediates of Glutathione with Polysulfides

D Liang, H Wu, MW Wong, D Huang - Organic letters, 2015 - ACS Publications
Diallyl trisulfide (DATS) reacts rapidly with glutathione (GSH) to release H2S through thiol–
disulfide exchange followed by allyl perthiol reduction by GSH. Yet diallyl disulfide (DADS) …

New fluorescent probes for sulfane sulfurs and the application in bioimaging

W Chen, C Liu, B Peng, Y Zhao, A Pacheco… - Chemical science, 2013 - pubs.rsc.org
A sulfane sulfur mediated benzodithiolone formation was developed. Based on this reaction,
two fluorescent probes (SSP1 and SSP2) for the detection of sulfane sulfur species …