Immune dysregulation in autism spectrum disorder: what do we know about it?

MA Robinson-Agramonte, E Noris García… - International journal of …, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a group of complex multifactorial neurodevelopmental
disorders characterized by a wide and variable set of neuropsychiatric symptoms, including …

Inflammation and neuro-immune dysregulations in autism spectrum disorders

D Siniscalco, S Schultz, AL Brigida, N Antonucci - Pharmaceuticals, 2018 - mdpi.com
Autism Spectrum Disorder (ASD) is characterized by persistent deficits in social
communication and interaction and restricted-repetitive patterns of behavior, interests, or …

Blood-brain barrier regulation in psychiatric disorders

J Kealy, C Greene, M Campbell - Neuroscience letters, 2020 - Elsevier
The blood-brain barrier (BBB) is a dynamic interface between the peripheral blood supply
and the cerebral parenchyma, controlling the transport of material to and from the brain …

A meta-analysis of pro-inflammatory cytokines in autism spectrum disorders: Effects of age, gender, and latitude

A Saghazadeh, B Ataeinia, K Keynejad… - Journal of psychiatric …, 2019 - Elsevier
Background Autism spectrum disorders (ASD) occur in 1.5% of the general population
worldwide. Studies suggest that ASD might have more costs than diabetes and attention …

Inflammatory mediators drive neuroinflammation in autism spectrum disorder and cerebral palsy

UTT Than, LT Nguyen, PH Nguyen, XH Nguyen… - Scientific Reports, 2023 - nature.com
Inflammation conditions are associated with autism spectrum disorder (ASD) and cerebral
palsy (CP), primarily observed in the peripheral immune system. However, the extent of …

[HTML][HTML] A powerful approach to estimating annotation-stratified genetic covariance via GWAS summary statistics

Q Lu, B Li, D Ou, M Erlendsdottir, RL Powles… - The American Journal of …, 2017 - cell.com
Despite the success of large-scale genome-wide association studies (GWASs) on complex
traits, our understanding of their genetic architecture is far from complete. Jointly modeling …

Association of peripheral blood levels of cytokines with autism spectrum disorder: A meta-analysis

H Zhao, H Zhang, S Liu, W Luo, Y Jiang… - Frontiers in psychiatry, 2021 - frontiersin.org
Background: Although increasing evidence suggests an association between alterations in
peripheral cytokines and autism spectrum disorder (ASD), a consensus is lacking. To …

Immune abnormalities in autism spectrum disorder—could they hold promise for causative treatment?

D Gładysz, A Krzywdzińska, KK Hozyasz - Molecular neurobiology, 2018 - Springer
Autism spectrum disorders (ASD) are characterized by impairments in language and
communication development, social behavior, and the occurrence of stereotypic patterns of …

Probiotic and oxytocin combination therapy in patients with autism spectrum disorder: a randomized, double-blinded, placebo-controlled pilot trial

XJ Kong, J Liu, K Liu, M Koh, H Sherman, S Liu, R Tian… - Nutrients, 2021 - mdpi.com
Autism spectrum disorder (ASD) is a rapidly growing neurodevelopmental disorder. Both
probiotics and oxytocin were reported to have therapeutic potential; however, the …

Gastrointestinal alterations in autism spectrum disorder: What do we know?

G Bjørklund, L Pivina, M Dadar, NA Meguid… - Neuroscience & …, 2020 - Elsevier
There is an emerging body of evidence associating children having autism spectrum
disorder (ASD) with gastrointestinal (GI) symptoms, such as abdominal pain, chronic …