Pulmonary hypertension (PH) is characterized by pulmonary artery remodeling that can
subsequently culminate in right heart failure and premature death. Emerging evidence …

Hypoxic pulmonary hypertension (PH) comprises a heterogeneous group of diseases
sharing the common feature of chronic hypoxia-induced pulmonary vascular remodeling …

It is now established that airway smooth muscle (ASM) has roles in determining airway
structure and function, well beyond that as the major contractile element. Indeed, changes in …

Hypoxia, characterized by reduced oxygen concentration, is a significant stressor that affects
the survival of aerobic species and plays a prominent role in cardiovascular diseases. From …

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-
transcriptionally. miRNAs can be induced by a variety of stresses such as hypoxia, and are …

MicroRNAs (miRNAs) are a class of small noncoding RNA which exert post-transcriptional
gene regulation activity by targeting messenger RNAs. miRNAs have been found to be …

Pulmonary arterial hypertension (PAH) is a devastating disease without effective treatment.
Despite decades of research and the development of novel treatments, PAH remains a fatal …

Pulmonary arterial hypertension (PAH) is a severe and increasingly prevalent disease,
manifested by the maladaptation of pulmonary vasculature, which consequently leads to …

Hypoxia is a central component of the tumor microenvironment and represents a major
source of therapeutic failure in cancer therapy. Recent work has provided a wealth of …

Abstract Iron–sulfur (Fe‐S) clusters are essential for mitochondrial metabolism, but their
regulation in pulmonary hypertension (PH) remains enigmatic. We demonstrate that …