Plasmid DNA for therapeutic applications in cancer

DH Martínez-Puente, JJ Pérez-Trujillo… - Pharmaceutics, 2022 - mdpi.com
Recently, the interest in using nucleic acids for therapeutic applications has been
increasing. DNA molecules can be manipulated to express a gene of interest for gene …

Potential molecular mechanisms of the anti-cancer activity of vitamin D

D Skrajnowska, B Bobrowska-Korczak - Anticancer research, 2019 - ar.iiarjournals.org
Vitamin D, or more precisely its active metabolite calcitriol (1, 25-(OH) 2D3), plays a
fundamental role in bone metabolism and differentiation as well as in intestinal absorption of …

Isolation and characterization of N‐(2‐Hydroxyethyl)hexadecanamide from Colletotrichum gloeosporioides with apoptosis‐inducing potential in breast cancer cells

N Rai, P Gupta, A Verma, SK Singh, V Gautam - BioFactors, 2023 - Wiley Online Library
Endophytic fungi are a well‐established reservoir of bioactive compounds that are
pharmaceutically valuable and therefore, contribute significantly to the biomedical field. The …

Human umbilical cord matrix-derived stem cells expressing interferon-β gene significantly attenuate bronchioloalveolar carcinoma xenografts in SCID mice

T Matsuzuka, RS Rachakatla, C Doi, DK Maurya… - Lung cancer, 2010 - Elsevier
Mesenchymal stem cells derived from the human umbilical cord matrix (hUCMSCs) have
great potential for therapeutic use for multiple diseases. The strategy that uses therapeutic …

[HTML][HTML] Recent Advances and Prospects of Nucleic Acid Therapeutics for Anti-Cancer Therapy

M Lee, M Lee, Y Song, S Kim, N Park - Molecules, 2024 - mdpi.com
Nucleic acid therapeutics are promising alternatives to conventional anti-cancer therapy,
such as chemotherapy and radiation therapy. While conventional therapies have limitations …

Over-expression of angiotensin II type 2 receptor gene induces cell death in lung adenocarcinoma cells

L Pickel, T Matsuzuka, C Doi, R Ayuzawa… - Cancer biology & …, 2010 - Taylor & Francis
The endogenous angiotensin II (Ang II) type 2 receptor (AT2) has been shown to mediate
apoptosis in cardiovascular tissues. Thus, the aim of this study was to explore the anti …

Apoptotic effects of valproic acid on miR-34a, miR-520h and HDAC1 gene in breast cancer

N Injinari, Z Amini-Farsani, M Yadollahi-Farsani… - Life Sciences, 2021 - Elsevier
Identifying miRNAs involved in cancer and devising strategies to control their expression is a
new therapeutic approach. Valproic acid (VPA) has attracted a lot of interest in cancer …

Relationship between IL-10 and tumor markers in breast cancer patients

L Llanes-Fernández, RI Álvarez-Goyanes… - The Breast, 2006 - Elsevier
Tumor markers are expressed due to molecular alterations of the tumor cells, and we can
relate them to the immune system to find new associations to improve prognosis. IL-10 …

Preparation and characterization of calcium-doped graphene oxide-chitosan Nanocarrier to enhance the gene delivery in MCF-7 cell line

AD Bidgoli, A Farmany, M Taheri, M Soleimani… - Scientific Reports, 2024 - nature.com
Gene delivery has emerged as a novel and effective method in the treatment of
malignancies within medical interventions by applying nanotechnology. Consequently, the …

Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation

W Li, MJ Hardwick, D Rosenthal, M Culty… - biochemical …, 2007 - Elsevier
The peripheral-type benzodiazepine receptor (PBR), an 18-kDa high affinity drug and
cholesterol binding protein, is expressed at high levels in various cancers. Its expression is …