Tumor microenvironment: barrier or opportunity towards effective cancer therapy
Tumor microenvironment (TME) is a specialized ecosystem of host components, designed
by tumor cells for successful development and metastasis of tumor. With the advent of 3D …
by tumor cells for successful development and metastasis of tumor. With the advent of 3D …
[HTML][HTML] 3D in vitro model (R) evolution: unveiling tumor–stroma interactions
The complex microenvironment in which malignant tumor cells grow is crucial for cancer
progression. The physical and biochemical characteristics of this niche are involved in …
progression. The physical and biochemical characteristics of this niche are involved in …
Tumor microenvironment signaling and therapeutics in cancer progression
Tumor development and metastasis are facilitated by the complex interactions between
cancer cells and their microenvironment, which comprises stromal cells and extracellular …
cancer cells and their microenvironment, which comprises stromal cells and extracellular …
3D bioprinting: from benches to translational applications
Over the last decades, the fabrication of 3D tissues has become commonplace in tissue
engineering and regenerative medicine. However, conventional 3D biofabrication …
engineering and regenerative medicine. However, conventional 3D biofabrication …
Could 3D models of cancer enhance drug screening?
Cancer is a multifaceted pathology, where cellular and acellular players interact to drive
cancer progression and, in the worst-case, metastasis. The current methods to investigate …
cancer progression and, in the worst-case, metastasis. The current methods to investigate …
Biomaterial-based platforms for tumour tissue engineering
Tissue engineering has produced innovative tools for cancer research. 3D cancer models
based on molecularly designed biomaterials aim to harness the dimensionality and …
based on molecularly designed biomaterials aim to harness the dimensionality and …
Flavonoids regulate tumor-associated macrophages–from structure-activity relationship to clinical potential
Q Sun, Q Liu, X Zhou, X Wang, H Li, W Zhang… - Pharmacological …, 2022 - Elsevier
In recent years, the strategy for tumor therapy has changed from focusing on the direct killing
effect of different types of therapeutic agents on cancer cells to the new mainstream of multi …
effect of different types of therapeutic agents on cancer cells to the new mainstream of multi …
Targeting tumor-associated macrophages for cancer immunotherapy
Y Shu, P Cheng - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2020 - Elsevier
Macrophages are important effector cells of the innate immune system and are also major
components of the tumor microenvironment (TME). Macrophages that are abundant in the …
components of the tumor microenvironment (TME). Macrophages that are abundant in the …
The role of biomaterials and scaffolds in immune responses in regenerative medicine: macrophage phenotype modulation by biomaterial properties and scaffold …
Scaffolds are an integral part of the regenerative medicine field. The contact of biomaterials
with tissue, as was clearly observed over the years, induces immune reactions in a material …
with tissue, as was clearly observed over the years, induces immune reactions in a material …
Recent progress of micro/nanorobots for cell delivery and manipulation
W Chen, H Zhou, B Zhang, Q Cao… - Advanced Functional …, 2022 - Wiley Online Library
Micro/nanorobots have attracted significant interest in the biomedical field due to their
micro/nano scale sizes and autonomously untethered motions. Meanwhile, stem cell‐based …
micro/nano scale sizes and autonomously untethered motions. Meanwhile, stem cell‐based …