The development of the concept of ferroptosis
T Hirschhorn, BR Stockwell - Free Radical Biology and Medicine, 2019 - Elsevier
The term ferroptosis was coined in 2012 to describe an iron-dependent regulated form of
cell death caused by the accumulation of lipid-based reactive oxygen species; this type of …
cell death caused by the accumulation of lipid-based reactive oxygen species; this type of …
Magnetic field effects in biology from the perspective of the radical pair mechanism
H Zadeh-Haghighi, C Simon - Journal of the Royal …, 2022 - royalsocietypublishing.org
Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …
biological systems. However, the underlying mechanisms behind these phenomena remain …
[HTML][HTML] Is depression associated with increased oxidative stress? A systematic review and meta-analysis
CN Black, M Bot, PG Scheffer, P Cuijpers… - …, 2015 - Elsevier
Background It has been suggested that depressed persons have increased oxidative stress
and decreased anti-oxidant defences. 8-Hydroxy-2′-deoxyguanosine (8-OHdG) and F2 …
and decreased anti-oxidant defences. 8-Hydroxy-2′-deoxyguanosine (8-OHdG) and F2 …
Bipolar disorder diagnosis: challenges and future directions
ML Phillips, DJ Kupfer - The Lancet, 2013 - thelancet.com
Bipolar disorder refers to a group of affective disorders, which together are characterised by
depressive and manic or hypomanic episodes. These disorders include: bipolar disorder …
depressive and manic or hypomanic episodes. These disorders include: bipolar disorder …
The role of mitochondria in mood disorders: from physiology to pathophysiology and to treatment
A Giménez-Palomo, S Dodd, G Anmella… - Frontiers in …, 2021 - frontiersin.org
Mitochondria are cellular organelles involved in several biological processes, especially in
energy production. Several studies have found a relationship between mitochondrial …
energy production. Several studies have found a relationship between mitochondrial …
Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a …
B Leonard, M Maes - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
This paper reviews that cell-mediated-immune (CMI) activation and inflammation contribute
to depressive symptoms, including anhedonia; anxiety-like behaviors; fatigue and somatic …
to depressive symptoms, including anhedonia; anxiety-like behaviors; fatigue and somatic …
Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors
There is now strong evidence of progressive neuropathological processes in bipolar
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …
A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro) degenerative processes in that …
This paper reviews the body of evidence that major depression is accompanied by a
decreased antioxidant status and by induction of oxidative and nitrosative (IO&NS) …
decreased antioxidant status and by induction of oxidative and nitrosative (IO&NS) …
Perineuronal nets protect fast-spiking interneurons against oxidative stress
JH Cabungcal, P Steullet, H Morishita… - Proceedings of the …, 2013 - National Acad Sciences
A hallmark of schizophrenia pathophysiology is the dysfunction of cortical inhibitory GABA
neurons expressing parvalbumin, which are essential for coordinating neuronal synchrony …
neurons expressing parvalbumin, which are essential for coordinating neuronal synchrony …
Meta-analysis of oxidative stress in schizophrenia
J Flatow, P Buckley, BJ Miller - Biological psychiatry, 2013 - Elsevier
Background Schizophrenia is associated with impaired antioxidant defense, including
abnormal serum, plasma, and red blood cell (RBC) oxidative stress parameters. We …
abnormal serum, plasma, and red blood cell (RBC) oxidative stress parameters. We …