The development of the concept of ferroptosis

T Hirschhorn, BR Stockwell - Free Radical Biology and Medicine, 2019 - Elsevier
The term ferroptosis was coined in 2012 to describe an iron-dependent regulated form of
cell death caused by the accumulation of lipid-based reactive oxygen species; this type of …

Magnetic field effects in biology from the perspective of the radical pair mechanism

H Zadeh-Haghighi, C Simon - Journal of the Royal …, 2022 - royalsocietypublishing.org
Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …

[HTML][HTML] Is depression associated with increased oxidative stress? A systematic review and meta-analysis

CN Black, M Bot, PG Scheffer, P Cuijpers… - …, 2015 - Elsevier
Background It has been suggested that depressed persons have increased oxidative stress
and decreased anti-oxidant defences. 8-Hydroxy-2′-deoxyguanosine (8-OHdG) and F2 …

Bipolar disorder diagnosis: challenges and future directions

ML Phillips, DJ Kupfer - The Lancet, 2013 - thelancet.com
Bipolar disorder refers to a group of affective disorders, which together are characterised by
depressive and manic or hypomanic episodes. These disorders include: bipolar disorder …

The role of mitochondria in mood disorders: from physiology to pathophysiology and to treatment

A Giménez-Palomo, S Dodd, G Anmella… - Frontiers in …, 2021 - frontiersin.org
Mitochondria are cellular organelles involved in several biological processes, especially in
energy production. Several studies have found a relationship between mitochondrial …

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a …

B Leonard, M Maes - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
This paper reviews that cell-mediated-immune (CMI) activation and inflammation contribute
to depressive symptoms, including anhedonia; anxiety-like behaviors; fatigue and somatic …

Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors

M Berk, F Kapczinski, AC Andreazza, OM Dean… - … & biobehavioral reviews, 2011 - Elsevier
There is now strong evidence of progressive neuropathological processes in bipolar
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …

A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro) degenerative processes in that …

M Maes, P Galecki, YS Chang, M Berk - Progress in Neuro …, 2011 - Elsevier
This paper reviews the body of evidence that major depression is accompanied by a
decreased antioxidant status and by induction of oxidative and nitrosative (IO&NS) …

Perineuronal nets protect fast-spiking interneurons against oxidative stress

JH Cabungcal, P Steullet, H Morishita… - Proceedings of the …, 2013 - National Acad Sciences
A hallmark of schizophrenia pathophysiology is the dysfunction of cortical inhibitory GABA
neurons expressing parvalbumin, which are essential for coordinating neuronal synchrony …

Meta-analysis of oxidative stress in schizophrenia

J Flatow, P Buckley, BJ Miller - Biological psychiatry, 2013 - Elsevier
Background Schizophrenia is associated with impaired antioxidant defense, including
abnormal serum, plasma, and red blood cell (RBC) oxidative stress parameters. We …