Traditional Chinese medicine reverses cancer multidrug resistance and its mechanism

J Wei, Z Liu, J He, Q Liu, Y Lu, S He, B Yuan… - Clinical and …, 2022 - Springer
Chemotherapy is one of the most commonly used clinical treatments among the currently
available cancer therapies. However, the phenomenon of Multidrug resistance (MDR) has …

[HTML][HTML] Emerging trends of phytochemicals as ferroptosis modulators in cancer therapy

F Khan, P Pandey, M Verma, S Ramniwas… - Biomedicine & …, 2024 - Elsevier
Ferroptosis, a novel form of regulated cell death characterized by dependence on iron and
lipid peroxidation, has been implicated in a wide range of clinical conditions including …

[HTML][HTML] Fuzheng Kang-Ai inhibits NSCLC cell proliferation via regulating hsa_circ_0048091/hsa-miR-378g/ARRDC3 pathway

Q Tang, X Wang, Q Zhou, Q Li, X Yang, M Xu, R Wang… - Phytomedicine, 2023 - Elsevier
Background Current treatments for lung cancer have their own deficiencies, such as severe
adverse effect. Therefore, more safe and effective drugs are needed. Purpose Fuzheng …

[HTML][HTML] A review on the research progress of traditional Chinese medicine with anti-cancer effect targeting ferroptosis

L Wang, H Huang, X Li, L Ouyang, X Wei, J Xie, D Liu… - Chinese Medicine, 2023 - Springer
Ferroptosis is a non-apoptotic form of regulated cell death characterized by iron-dependent
lipid peroxidation. It can be triggered by various mechanisms, including the glutathione …

[HTML][HTML] GPX4 plays a crucial role in Fuzheng Kang'ai decoction-induced non-small cell lung cancer cell ferroptosis

YY Zhao, YQ Yang, HH Sheng, Q Tang… - Frontiers in …, 2022 - frontiersin.org
Background: Fuzheng Kang'ai decoction (FZKA) has been widely used to treat Non-Small
Cell Lung Cancer (NSCLC) patients in China for decades, showing definitively curative …

[HTML][HTML] Compound Kushen Injection Protects Skin From Radiation Injury via Regulating Bim

J Zheng, G Li, J Wang, S Wang, Q Tang… - Frontiers in …, 2021 - frontiersin.org
Background: Radiation-induced skin injury is a major side-effect observed in cancer patients
who received radiotherapy. Thus identifying new radioprotective drugs for prevention or …

[HTML][HTML] Fuzheng Kang'ai decoction (扶正抗癌方) inhibits cell proliferation, migration and invasion by modulating mir-21-5p/human phosphatase and tensin homology …

LI Jinhua, L Chunping, Z Yueyang… - Journal of Traditional …, 2022 - ncbi.nlm.nih.gov
OBJECTIVE: To elucidate the potential molecular mechanism by which Fuzheng Kang'ai
decoction (扶正抗癌方, FZKA) inhibits proliferation, migration, and invasion of lung cancer …

[HTML][HTML] ICT1 Promotes osteosarcoma cell proliferation and inhibits apoptosis via STAT3/BCL-2 pathway

X Pan, J Tan, X Weng, R Du, Y Jiang, Y Weng… - BioMed Research …, 2021 - hindawi.com
Osteosarcoma (OS) is a familiar malignant bone tumor that occurs mainly in adolescents.
Immature colon carcinoma transcript-1 (ICT1) is an important member of the large …

Effects of Citrus aurantium L. on Gastrointestinal Motility and Gastric Cancer Cell Proliferation

M Gao, W Yang - Cancer Biotherapy & Radiopharmaceuticals, 2023 - liebertpub.com
Background: To research the impact of a Chinese traditional medicine (Citrus aurantium L.)
on gastric cancer proliferation and mice gastrointestinal motility. Materials and Methods: The …

Fuzheng Kang-Ai decoction increases the sensitivity of Gefitinib via inducing Non-Small Cell Lung Cancer ferroptosis through AMPK/SLC7A11 pathway

YY Zhao, MF Xu, SJ Wang, NX Zhong, SH Qiu, Q Tang… - 2023 - researchsquare.com
Background: Fuzheng Kang-Ai decoction (FZKA), which consists of twelve Chinese herbal
medicines (CHM), has been extensively used in the treatment of Non-Small Cell Lung …