Computational modeling techniques and computer simulations have become a routine in
biological sciences and have gained great attention from researchers. Molecular dynamics …

Specific antibody-antigen recognition is crucial for the immune response. Knowledge of
molecular interaction details in the recognition process is fundamental for the rational design …

Eucb is a standalone program for geometrical analysis of molecular dynamics trajectories of
protein systems. The program is written in GNU C++ and it can be installed in any operating …

Oligomeric amyloid β (A β) is currently considered the most neurotoxic form of the A β
peptide implicated in Alzheimer's disease (AD). The molecular structures of the oligomers …

Upregulated phosphodiesterase 4D (PDE4D) disrupts the regulation of calcium ion channel
in the central nerve system, and hence it is considered as one of the causes of Alzheimer's …

Human MUC1 is over-expressed in human adenocarcinomas and has been used as a
target for immunotherapy studies. The 9-mer MUC1-9 peptide has been identified as one of …

Diante da relevância dos casos de câncer no mundo, o estudo de alternativas para o
tratamento é de extrema importância, e uma delas é a obtenção de anticorpos monoclonais …

Alzheimer's disease (AD) is the most common cause of cognitive impairment. It is
characterized by the presence of plaques in the brain consisting of protein fragments called …

Pvs25 is a protein of unique 3D structure, and it is characterized by the presence of repeated
EGF-like domains and 11 disulfide bonds. It is a very important candidate for the …

Anticorpos de cadeia pesada única derivados de camelídeos (HCAb) utilizam o domínio
variável N-terminal para estabelecer a interação com o antígeno. Quando isolado, este …