The sustained and/or targeted delivery of hydrophilic drugs is an important field within drug
delivery, presenting unique challenges when compared to that of hydrophobic drugs. Yet …

Poor aqueous solubility of drugs is still a foremost challenge in pharmaceutical product
development. The use of lipids in designing formulations provides an opportunity to …

A suitable drug-loaded implant delivery system that can effectively release antibacterial drug
in the postoperative lesion area and help repair bone infection is very significant in the …

Osteoporosis is defined as a systemic skeletal disease characterized by low bone mass and
microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility …

The aim of this study is to design and evaluate a transdermal delivery system for
alendronate sodium (ALS) loaded with nanocarrier to improve its permeability and prolong …

Bone metastasis has been considered the fatal phase of cancers, which remains incurable
and to be a challenge due to the non-availability of the ideal treatment strategy. Unlike bone …

Formulation is a crucial stage in drug development since it determines the best formula. The
quality of the preparation is good and fulfills the standard parameters when using the best …

Background: At present, the controlled local drug delivery is a very promising approach
compared to systemic administration, since it mostly targets the affected tissue. In fact …

The idea to go for this review is to collect the recent data by focusing on the supramolecular
gel. The design of supramolecular gel and its various applications have received growing …

Systemic administration of alendronate is associated with various adverse reactions in
clinical settings. To mitigate these side effects, poloxamer 407 (P-407) modified with …