Edema is an accumulation of fluid in the interstitial space that occurs as the capillary filtration
exceeds the limits of lymphatic drainage, producing noticeable clinical signs and symptoms …

Many drugs are responsible, through different mechanisms, for peripheral oedema. Severity
is highly variable, ranging from slight oedema of the lower limbs to anasarca pictures as in …

The original KDIGO Clinical Practice Guideline for the Management of Blood Pressure in
Chronic Kidney Disease in the chronic kidney disease (CKD) population not receiving …

Importance Calcium channel blockers (CCBs) are commonly prescribed agents for
hypertension that can cause peripheral edema. A prescribing cascade occurs when the …

High blood pressure is the world's leading cause of death, but despite treatment for
hypertension being safe, effective, and low cost, most people with hypertension worldwide …

Objectives Isradipine is a dihydropyridine calcium channel inhibitor that has demonstrated
concentration‐dependent neuroprotective effects in animal models of Parkinson's disease …

Dihydropyridine calcium channel blockers (DHPCCBs) are widely used to treat hypertension
and chronic coronary artery disease. One common adverse effect of DHPCCBs is peripheral …

Importance Calcium channel blockers, specifically dihydropyridine calcium channel blockers
(DH CCBs, eg, amlodipine), may cause lower-extremity edema. Anecdotal reports suggest …

Effective treatment of high blood pressure (BP) represents a key strategy for reducing the
burden of hypertension-related cardiovascular and renal diseases. In spite of these well …

Background Prescribing cascades are a source of inappropriate prescribing for older adults
with dementia. We aimed to study three prescribing cascades in older Nova Scotians with …