Dystrophin is a long rod-shaped protein that connects the subsarcolemmal cytoskeleton to a
complex of proteins in the surface membrane (dystrophin protein complex, DPC), with further …

Triglyceride storage is altered across various chronic health conditions necessitating various
techniques to visualize and quantify lipid droplets (LDs). Here, we describe the utilization of …

The absence of dystrophin in Duchenne muscular dystrophy disrupts the dystrophin-
associated glycoprotein complex resulting in skeletal muscle fiber fragility and atrophy …

Muscle cell fusion is a multistep process involving cell migration, adhesion, membrane
remodeling and actin-nucleation pathways to generate multinucleated myotubes. However …

Dysferlinopathies, most commonly limb girdle muscular dystrophy 2B and Miyoshi
myopathy, are degenerative myopathies caused by mutations in the DYSF gene encoding …

The function of many organs, including skeletal muscle, depends on their three-dimensional
structure. Muscle regeneration therefore requires not only reestablishment of myofibers but …

Key points• Strength loss induced by lengthening contractions is typically attributed to
damaged force‐bearing structures within skeletal muscle. Muscle lacking the structural …

Muscular dystrophies are genetically diverse but share common phenotypic features of
muscle weakness, degeneration, and progressive decline in muscle function. Previous work …

Duchenne muscular dystrophy (DMD) is a devastating neuromuscular disease in which
weakness, increased susceptibility to muscle injury, and inadequate repair appear to …

Background Excess reactive oxygen species (ROS) and muscle weakness occur in parallel
in multiple pathological conditions. However, the causative role of skeletal muscle …