Oxidation and age-related macular degeneration: insights from molecular biology

S Khandhadia, A Lotery - Expert reviews in molecular medicine, 2010 - cambridge.org
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed
world. It is a multifactorial disease, and current therapy predominantly limits damage only …

Oxidative stress and its downstream signaling in aging eyes

MD Pinazo-Durán, R Gallego-Pinazo… - … interventions in aging, 2014 - Taylor & Francis
Background Oxidative stress (OS) and its biomarkers are the biochemical end point of the
imbalance between reactive oxygen species (ROS) production and the ability of the …

Role of early life exposure and environment on neurodegeneration: implications on brain disorders

S Modgil, DK Lahiri, VL Sharma, A Anand - Translational …, 2014 - Springer
Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD),
Amyotrophic lateral sclerosis (ALS) and retinal degeneration have been studied extensively …

Chlorogenic and caftaric acids in liver toxicity and oxidative stress induced by methamphetamine

KMM Koriem, RE Soliman - Journal of toxicology, 2014 - Wiley Online Library
Methamphetamine intoxication can cause acute hepatic failure. Chlorogenic and caftaric
acids are the major dietary polyphenols present in various foods. The aim of this study was …

Supraphysiologic-dose anabolic–androgenic steroid use: A risk factor for dementia?

MJ Kaufman, G Kanayama, JI Hudson… - … & Biobehavioral Reviews, 2019 - Elsevier
Supraphysiologic-dose anabolic-androgenic steroid (AAS) use is associated with
physiologic, cognitive, and brain abnormalities similar to those found in people at risk for …

HIV neuropathogenesis in the presence of a disrupted dopamine system

EA Nickoloff-Bybel, TM Calderon, PJ Gaskill… - Journal of Neuroimmune …, 2020 - Springer
Antiretroviral therapy (ART) has transformed HIV into a chronic condition, lengthening and
improving the lives of individuals living with this virus. Despite successful suppression of HIV …

Eclectic ocular comorbidities and systemic diseases with eye involvement: a review

MD Pinazo-Durán, V Zanón-Moreno… - BioMed research …, 2016 - Wiley Online Library
Coexistence of several ocular diseases is more frequent than suspected. In spite of the
refractive errors, one or more of the following can be detected simultaneously: glaucoma …

The role of equilibrium between free radicals and antioxidants in depression and bipolar disorder

A Kotzaeroglou, I Tsamesidis - Medicines, 2022 - mdpi.com
Background: Increasing evidence suggests that the presence of oxidative stress and
disorders of the antioxidant defense system are involved in a wide range of neuropsychiatric …

Oxidative stress status in recently abstinent methamphetamine abusers

MC Huang, SK Lin, CH Chen, CH Pan… - Psychiatry and …, 2013 - Wiley Online Library
Aim Methamphetamine (METH) administration is associated with excessive oxidative stress.
It is not known whether the systemic oxidative stress indices would alter during early …

Protective effects of alpha-lipoic acid on anxiety-like behavior, memory and prevention of hippocampal oxidative stress in methamphetamine-treated rats

HMP Kargar, H Noshiri - Psychopharmacology, 2024 - Springer
Rationale Alpha-lipoic acid is an essential cofactor for aerobic metabolism and acts as a
potent antioxidant in the body. It has been shown that acute exposure to methamphetamine …