EANO guideline on the diagnosis and management of meningiomas

R Goldbrunner, P Stavrinou, MD Jenkinson… - Neuro …, 2021 - academic.oup.com
Meningiomas are the most common intracranial tumors. Yet, only few controlled clinical trials
have been conducted to guide clinical decision making, resulting in variations of …

An overview of meningiomas

RA Buerki, CM Horbinski, T Kruser, PM Horowitz… - Future …, 2018 - Taylor & Francis
Meningiomas are the most common primary intracranial tumor. Important advances are
occurring in meningioma research. These are expected to accelerate, potentially leading to …

EANO guidelines for the diagnosis and treatment of meningiomas

R Goldbrunner, G Minniti, M Preusser… - The Lancet …, 2016 - thelancet.com
Although meningiomas are the most common intracranial tumours, the level of evidence to
provide recommendations for the diagnosis and treatment of meningiomas is low compared …

Response assessment in neuro-oncology clinical trials

PY Wen, SM Chang, MJ Van den Bent… - Journal of Clinical …, 2017 - ascopubs.org
Development of novel therapies for CNS tumors requires reliable assessment of response
and progression. This requirement has been particularly challenging in neuro-oncology for …

Signaling pathways in brain tumors and therapeutic interventions

S Li, C Wang, J Chen, Y Lan, W Zhang… - … and Targeted Therapy, 2023 - nature.com
Brain tumors, although rare, contribute to distinct mortality and morbidity at all ages.
Although there are few therapeutic options for brain tumors, enhanced biological …

Meningioma: not always a benign tumor. A review of advances in the treatment of meningiomas

I Maggio, E Franceschi, A Tosoni, VD Nunno… - CNS …, 2021 - Taylor & Francis
Meningiomas are the most common primary intracranial tumors. The majority of
meningiomas are benign, but they can present different grades of dedifferentiation from …

Phase 2 study of pembrolizumab in patients with recurrent and residual high-grade meningiomas

PK Brastianos, AE Kim, A Giobbie-Hurder… - Nature …, 2022 - nature.com
High-grade meningiomas are associated with neuro-cognitive morbidity and have limited
treatments. High-grade meningiomas harbor an immunosuppressive tumor …

Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma

M Abedalthagafi, WL Bi, AA Aizer, PH Merrill… - Neuro …, 2016 - academic.oup.com
Background Meningiomas are the most common primary intracranial tumor in adults.
Identification of SMO and AKT1 mutations in meningiomas has raised the possibility of …

Detection of diagnostic and prognostic methylation-based signatures in liquid biopsy specimens from patients with meningiomas

GA Herrgott, JM Snyder, R She, TM Malta… - Nature …, 2023 - nature.com
Recurrence of meningiomas is unpredictable by current invasive methods based on
surgically removed specimens. Identification of patients likely to recur using noninvasive …

Advances in meningioma genetics: novel therapeutic opportunities

M Preusser, PK Brastianos, C Mawrin - Nature Reviews Neurology, 2018 - nature.com
Meningiomas currently are among the most frequent intracranial tumours. Although the
majority of meningiomas can be cured by surgical resection,∼ 20% of patients have an …