The progress in understanding and treatment of diabetic retinopathy
Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and
remains a leading cause of vision loss globally. Its aetiology and pathology have been …
remains a leading cause of vision loss globally. Its aetiology and pathology have been …
New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism
Diabetes adversely affects multiple organs, including the kidney, eye and nerve, leading to
diabetic kidney disease, diabetic retinopathy and diabetic neuropathy, respectively. In both …
diabetic kidney disease, diabetic retinopathy and diabetic neuropathy, respectively. In both …
Wnt Signaling in vascular eye diseases
The Wnt signaling pathway plays a pivotal role in vascular morphogenesis in various organs
including the eye. Wnt ligands and receptors are key regulators of ocular angiogenesis both …
including the eye. Wnt ligands and receptors are key regulators of ocular angiogenesis both …
Lipid metabolism dysregulation in diabetic retinopathy
JV Busik - Journal of lipid research, 2021 - ASBMB
Lipid metabolic abnormalities have emerged as potential risk factors for the development
and progression of diabetic complications, including diabetic retinopathy (DR). This review …
and progression of diabetic complications, including diabetic retinopathy (DR). This review …
Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPARα
Fenofibrate, a specific agonist of peroxisome proliferator–activated receptor-α (PPARα),
displays robust therapeutic effects on diabetic retinopathy (DR) in patients with type 2 …
displays robust therapeutic effects on diabetic retinopathy (DR) in patients with type 2 …
Pericytes, inflammation, and diabetic retinopathy
BG Spencer, JJ Estevez, E Liu, JE Craig… - …, 2020 - Springer
Diabetic retinopathy (DR) is a frequent complication of diabetes mellitus, and a common
cause of vision impairment and blindness in these patients, yet many aspects of its …
cause of vision impairment and blindness in these patients, yet many aspects of its …
Vascular pericyte impairment and connexin43 gap junction deficit contribute to vasomotor decline in diabetic retinopathy
E Ivanova, T Kovacs-Oller… - Journal of …, 2017 - Soc Neuroscience
Adequate blood flow is essential to brain function, and its disruption is an early indicator in
diseases, such as stroke and diabetes. However, the mechanisms contributing to this …
diseases, such as stroke and diabetes. However, the mechanisms contributing to this …
Fenofibrate ameliorates diabetic retinopathy by modulating Nrf2 signaling and NLRP3 inflammasome activation
Oxidative stress and neuroinflammation contribute significantly to the development and
progression of diabetic retinopathy. Fenofibrate has received great attention as it benefits …
progression of diabetic retinopathy. Fenofibrate has received great attention as it benefits …
The Effect of Hyperlipidemia on the Course of Diabetic Retinopathy—Literature Review
A Bryl, M Mrugacz, M Falkowski, K Zorena - Journal of clinical medicine, 2022 - mdpi.com
Diabetes mellitus is a very important social issue, and its retinal complications continue to be
one of the major causes of blindness worldwide. The effect of glucose level on the …
one of the major causes of blindness worldwide. The effect of glucose level on the …
Peroxisome proliferator-activated receptor-α (PPARα) regulates wound healing and mitochondrial metabolism in the cornea
Diabetes can result in impaired corneal wound healing. Mitochondrial dysfunction plays an
important role in diabetic complications. However, the regulation of mitochondria function in …
important role in diabetic complications. However, the regulation of mitochondria function in …