Pertussis (whooping cough) epidemics persist globally despite high vaccine coverage
among infants and young children. The resurgence of pertussis in high-income countries is …

Objective Countries routinely offering acellular pertussis vaccine, where long-term protection
is not sustained, have the challenge of selecting an optimal schedule to minimise disease …

Abstract Background In March 2020, England went into its first lockdown in response to the
COVID-19 pandemic. Restrictions eased temporarily, followed by second and third waves in …

The resurgence of pertussis over the past decades has resulted in incidence levels not
witnessed in the United States since the 1950s. The underlying causes have been the …

Background Pertussis vaccination in pregnancy is recommended in many countries to
provide protection to young infants. The best timing for this vaccination is uncertain. In the …

OBJECTIVES: To determine pertussis risk by diphtheria-tetanus-acellular pertussis (DTaP)
vaccination status and time since last DTaP dose. METHODS: Children born at Kaiser …

Background Immunogenicity of acellular pertussis (aP) vaccines is conventionally assessed
by measuring antibody responses but antibody concentrations wane quickly after …

Immunization with current acellular pertussis (aP) vaccines protects against severe
pertussis, but immunity wanes rapidly after vaccination and these vaccines do not prevent …

Importance The United States has experienced a nationwide resurgence of pertussis since
the mid-1970s, despite high estimated vaccine coverage. Short-lived immunity induced by …

Pertussis, which is caused by Bordetella pertussis, has plagued humans for at least 800
years, is highly infectious and can be fatal in the unvaccinated, especially very young …