The mechanism of the cadmium-induced toxicity and cellular response in the liver

V Souza-Arroyo, JJ Fabián, L Bucio-Ortiz… - Toxicology, 2022 - Elsevier
Cadmium is a toxic element to which man can be exposed at work or in the environment.
Cd's most salient toxicological property is its exceptionally long half-life in the human body …

[HTML][HTML] Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

AC Famurewa, K Renu, MA Eladl… - Biomedicine & …, 2022 - Elsevier
Toxic heavy metals (THMs) are non-essential hazardous environmental pollutants with
intractable health challenges in humans and animals. Exposure to lead (Pb), cadmium (Cd) …

Hesperidin protects liver and kidney against sodium fluoride-induced toxicity through anti-apoptotic and anti-autophagic mechanisms

C Caglayan, FM Kandemir, E Darendelioğlu… - Life Sciences, 2021 - Elsevier
Aim High dose of fluoride intake is associated with toxic effects on liver and kidney tissues.
One approach to tackle these toxicities is using natural antioxidants as supplements. This …

[HTML][HTML] Independent, combine and interactive effects of heavy metal exposure on dyslipidemia biomarkers: a cross-sectional study in northeastern China

M Zhao, G Yin, J Xu, X Ge, A Li, Y Mei, J Wu… - Ecotoxicology and …, 2023 - Elsevier
Dyslipidemia is a common disease in the older population and represents a considerable
disease burden worldwide. Epidemiological and experimental studies have indicated …

Modulatory effects of carvacrol against cadmium-induced hepatotoxicity and nephrotoxicity by molecular targeting regulation

FM Kandemir, C Caglayan, E Darendelioğlu… - Life Sciences, 2021 - Elsevier
Abstract Aim Cadmium (Cd) is a toxic heavy metal that causes severe toxic effects on
different tissues including liver and kidney. Therefore the research for alternatives to reduce …

Hepatoprotective and cognitive-enhancing effects of hesperidin against thioacetamide-induced hepatic encephalopathy in rats

NFA El-Magd, DH El-Kashef, M El-Sherbiny, SM Eraky - Life Sciences, 2023 - Elsevier
Hepatic encephalopathy (HE) is a serious neurological disorder which might occur in both
acute and chronic liver injury. Aims: This study was carried out to explore the protective …

Citrus species: Modern functional food and nutraceutical-based product ingredient

M Leporini, R Tundis, V Sicari, MR Loizzo - Italian Journal of Food Science, 2021 - itjfs.com
Citrus is the most cultivated fruit crop in the world and occupies a place of considerable
importance in the country's economy. Almost 33% of the citrus fruits are processed for juice …

[HTML][HTML] New insights into therapeutic applications and nanoformulation approaches of Hesperidin: An updated review

K Bansal, H Bhati, M Bajpai - Pharmacological Research-Modern …, 2024 - Elsevier
Introduction Hesperidin is a flavanone glycoside occurring in high levels in citrus species. It
is among the most significant natural anti-oxidants employed often in pharmaceuticals for …

Hesperidin supplementation improves altered PON-1, LDL oxidation, inflammatory response and hepatic function in an experimental rat model of hyperlipidemia

R Kumar, MI Khan, F Ashfaq, AA Alsayegh… - Indian Journal of Clinical …, 2024 - Springer
In this study, we have examined the effect of hesperidin on rats fed on an experimental high-
fat diet. Male Wistar rats were given a high-fat diet orally for one month for developing an …

Harnessing the power of Arctium lappa root: a review of its pharmacological properties and therapeutic applications

M Shyam, EP Sabina - Natural Products and Bioprospecting, 2024 - Springer
Arctium lappa, widely recognized as burdock, is a perennial plant that is employed in the
realm of traditional Chinese medicine for a wide range of medicinal applications. The herb is …