Circular RNAs in the pathogenesis of atherosclerosis

Q Cao, Z Guo, S Du, H Ling, C Song - Life sciences, 2020 - Elsevier
Atherosclerosis is a common cause of cardiovascular and cerebrovascular diseases.
Noncoding RNAs (ncRNAs), including microRNAs (miRNAs), long noncoding RNAs …

Non-coding RNAs: the extensive and interactive regulators of the blood-brain barrier permeability

R Yang, B Xu, B Yang, J Fu, H Chen, X Wang - RNA biology, 2021 - Taylor & Francis
The blood-brain barrier (BBB), which controls permeability into and out of the nervous
system, is a tightly connected, structural, and functional separation between the central …

[HTML][HTML] Up-regulation of circARF3 reduces blood-brain barrier damage in rat subarachnoid hemorrhage model via miR-31-5p/MyD88/NF-κB axis

L Cai, B Ge, S Xu, X Chen, H Yang - Aging (albany NY), 2021 - ncbi.nlm.nih.gov
Inflammation events have been found to aggravate brain injury and blood-brain barrier
(BBB) damage following subarachnoid hemorrhage (SAH). This study probed the role and …

Circular RNAs in early brain development and their influence and clinical significance in neuropsychiatric disorders

CJ Zhuo, WH Hou, DG Jiang, HJ Tian… - Neural regeneration …, 2020 - journals.lww.com
Neuropsychiatric disorders represent a set of severe and complex mental illnesses, and the
exact etiologies of which are unknown. It has been well documented that impairments in the …

Disease‐Associated Circular RNAs: From Biology to Computational Identification

M Tang, L Kui, G Lu, W Chen - BioMed Research International, 2020 - Wiley Online Library
Circular RNAs (circRNAs) are endogenous RNAs with a covalently closed continuous loop,
generated through various backsplicing events of pre‐mRNA. An accumulating number of …

New insights into circRNA and its mechanisms in angiogenesis regulation in ischemic stroke: a biomarker and therapeutic target

L Cheng, Z Liu, J Xia - Molecular Biology Reports, 2023 - Springer
Ischemic stroke accounts for about 71% of strokes worldwide. Due to limited recommended
therapeutics for ischemic stroke, more attention is focused on angiogenesis in ischemic …

Differential expression and correlation analysis of global transcriptome for hemorrhagic transformation after acute ischemic stroke

R Han, P Zhang, H Li, Y Chen, Y Hao, Q Guo… - Frontiers in …, 2022 - frontiersin.org
In order to explore the epigenetic characteristics of hemorrhagic transformation (HT) after
acute ischemic stroke, we used transcriptome sequencing technology to analyze the global …

Expression and function of circular RNAs in the mammalian brain

K Xu, Y Zhang, J Li - Cellular and Molecular Life Sciences, 2021 - Springer
Mammalian brain presents extraordinary complexity reflected in the structure, function, and
dynamic changes in the biological and physiological processes of development, maturity …

The circ_006573/miR-376b-3p Axis Advances Spinal Cord Functional Recovery after Injury by Modulating Vascular Regeneration

K Wang, X Su, Q Song, Z Chen, H Chen, Y Han… - Molecular …, 2023 - Springer
Abnormal expression of non-coding RNAs after spinal cord injury (SCI) is associated with
pathophysiological outcomes. We bioinformatically predicted a circRNA-miRNA-mRNA axis …

CircRNA and Stroke: New Insight of Potential Biomarkers and Therapeutic Targets

XL Chen, QD Tan, KJ Chen, DN Zheng… - Neurochemical …, 2024 - Springer
Stroke, the second-largest cause of death and the leading cause of disability globally,
presents significant challenges in terms of prognosis and treatment. Identifying reliable …