Abstract Background/Objectives: The Management of Myelomeningocele (MMC) Study
(MOMS) showed that prenatal repair of MMC resulted in improved neurological outcomes …

Hydrocephalus is classically considered as a failure of cerebrospinal fluid (CSF)
homeostasis that results in the active expansion of the cerebral ventricles. Infants with …

Background Previous reports from the Management of Myelomeningocele Study
demonstrated that prenatal repair of myelomeningocele reduces hindbrain herniation and …

METHODS: Follow-up cohort study of 161 children enrolled in MOMS. Assessments
included neuropsychological and physical evaluations. Children were evaluated at a MOMS …

The B cell response to Salmonella typhimurium (STm) occurs massively at extrafollicular
sites, without notable germinal centers (GCs). Little is known in terms of its specificity. To …

Importance The Management of Myelomeningocele Study (MOMS), a randomized clinical
trial of prenatal vs standard postnatal repair for myelomeningocele, found that prenatal …

Myelomeningocele (MMC) is the most frequently occurring congenital abnormality of the
central nervous system and leads to significant physical disabilities. Historically treatment …

ABSTRACT Objective The Management of Myelomeningocele Study (MOMS) trial
demonstrated the safety and efficacy of open fetal surgery for spina bifida aperta (SBA) …

Objective This revised guideline is intended to provide an update on the genetic aspects,
prevention, screening, diagnosis, and management of fetal neural tube defects. Target …

Spina bifida is a congenital central nervous system malformation caused by incomplete
closure of the neural tube by 28 days of gestation, leading to a defect in the bony spine. The …