Spheroid formation and peritoneal metastasis in ovarian cancer: the role of stromal and immune components

M Rakina, A Kazakova, A Villert, L Kolomiets… - International journal of …, 2022 - mdpi.com
Ovarian cancer (OC) is one of the most common gynecological cancers, with the worst
prognosis and the highest mortality rate. Peritoneal dissemination (or carcinomatosis) …

Identification of collagen genes related to immune infiltration and epithelial-mesenchymal transition in glioma

W Yin, H Zhu, J Tan, Z Xin, Q Zhou, Y Cao, Z Wu… - Cancer Cell …, 2021 - Springer
Background Gliomas account for the majority of fatal primary brain tumors, and there is much
room for research in the underlying pathogenesis, the multistep progression of glioma, and …

Profiling ovarian cancer tumor and microenvironment during disease progression for cell-based immunotherapy design

YR Li, CJ Ochoa, Y Zhu, A Kramer, M Wilson, Y Fang… - Iscience, 2023 - cell.com
Ovarian cancer (OC) is highly lethal due to late detection and frequent recurrence. Initial
treatments, comprising surgery and chemotherapy, lead to disease remission but are …

CACNA1C is a prognostic predictor for patients with ovarian cancer

X Chang, Y Dong - Journal of Ovarian Research, 2021 - Springer
Background CACNA1C, as a type of voltage-dependent calcium ion transmembrane
channel, played regulatory roles in the development and progress of multiple tumors. This …

Development and validation of a TNF family‐based signature for predicting prognosis, tumor immune characteristics, and immunotherapy response in colorectal …

Z Xiao, K Nie, T Han, L Cheng, Z Zhang… - Journal of …, 2021 - Wiley Online Library
In this study, a comprehensive analysis of TNF family members in colorectal cancer (CRC)
was conducted and a TNF family‐based signature (TFS) was generated to predict prognosis …

Genomic analysis of TNF-related genes with prognosis and characterization of the tumor immune microenvironment in lung adenocarcinoma

H Huang, H Yu, X Li, Y Li, G Zhu, L Su, M Li… - Frontiers in …, 2022 - frontiersin.org
Background The tumor necrosis factor (TNF) family plays a role in modulating cellular
functions that regulate cellular differentiation, survival, apoptosis, and especially cellular …

Cancer associated fibroblasts serve as an ovarian cancer stem cell niche through noncanonical Wnt5a signaling

Y Fang, X Xiao, J Wang, S Dasari, D Pepin… - NPJ Precision …, 2024 - nature.com
Frequent relapse and chemoresistance cause poor outcome in ovarian cancer (OC) and
cancer stem cells (CSCs) are important contributors. While most studies focus exclusively on …

[HTML][HTML] Association of TNFRSF19 with a TNF family-based prognostic model and subtypes in gliomas using machine learning

Y Guo, Q Zhou, M Wei, J Fan, H Huang - Heliyon, 2024 - cell.com
Purpose TNF family members (TFMs) play a crucial role in different types of cancers, with
TNF Receptor Superfamily Member 19 (TNFRSF19) standing out as a particularly important …

[HTML][HTML] Meta-analysis identifying epithelial-derived transcriptomes predicts poor clinical outcome and immune infiltrations in ovarian cancer

D Li, A Tulahong, MN Uddin, H Zhao… - Mathematical …, 2021 - aimspress.com
Previous studies revealed that the epithelial component is associated with the modulation of
the ovarian tumor microenvironment (TME). However, the identification of key transcriptional …

TBC1D2 Promotes Ovarian Cancer Metastasis via Inducing E-Cadherin Degradation

J Tian, X Liang, D Wang, J Tian, H Liang, T Lei… - Frontiers in …, 2022 - frontiersin.org
Background Ovarian cancer (OC) is the most lethal gynecological malignancy worldwide.
Increasing evidence indicates that TBC domain family is implicated in various cellular events …