Formation of nitrogen-containing six-membered heterocycles on steroidal ring system: A review
K Sharma, H Kumar - Steroids, 2023 - Elsevier
Steroidal heterocyclic compounds constitute interesting and promising scaffolds for drug
discovery as they have displayed diverse chemical reactivity and several types of biological …
discovery as they have displayed diverse chemical reactivity and several types of biological …
Fused and substituted pyrimidine derivatives as profound anti-cancer agents
N Abbas, GSP Matada, PS Dhiwar… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
The rationale behind drug design is the strategic utilization of heterocyclic fragments with
specific physicochemical properties to form molecular targeted agents. Among the …
specific physicochemical properties to form molecular targeted agents. Among the …
Exosome-mediated transfer of cancer cell resistance to antiestrogen drugs
Exosomes are small vesicles which are produced by the cells and released into the
surrounding space. They can transfer biomolecules into recipient cells. The main goal of the …
surrounding space. They can transfer biomolecules into recipient cells. The main goal of the …
Fe (iii)-Catalyzed synthesis of steroidal imidazoheterocycles as potent antiproliferative agents
An efficient and practical method has been developed for the synthesis of steroidal
imidazoheterocycles via cost-effective and environmentally benign FeCl3-catalyzed …
imidazoheterocycles via cost-effective and environmentally benign FeCl3-catalyzed …
Discovery of highly potent proapoptotic antiestrogens in a series of androst-5, 16-dienes D-modified with imidazole-annulated pendants
V Birukova, A Scherbakov, A Ilina, D Salnikova… - The Journal of Steroid …, 2023 - Elsevier
Heterocyclic derivatives of steroid hormones are potent anticancer agents, which are used in
the chemotherapy of breast and prostate cancers. Here, we describe a novel series of …
the chemotherapy of breast and prostate cancers. Here, we describe a novel series of …
Novel steroidal 1, 3, 4-thiadiazines: Synthesis and biological evaluation in androgen receptor-positive prostate cancer 22Rv1 cells
AS Komendantova, AM Scherbakov, AV Komkov… - Bioorganic …, 2019 - Elsevier
A flexible approach to previously unknown spirofused and linked 1, 3, 4-thiadiazine
derivatives of steroids with selective control of heterocyclization patterns is disclosed.(N …
derivatives of steroids with selective control of heterocyclization patterns is disclosed.(N …
[HTML][HTML] Synthesis, biological evaluation and molecular docking of pyrimidine and quinazoline derivatives of 1, 5-benzodiazepine as potential anticancer agents
A new series of Pyrimidine (A, D and F) and quinazoline (B, C and E) analogues of 1, 5-
benzodiazepines were prepared via its nitrile-derived amidoximes in and nitrilium ions …
benzodiazepines were prepared via its nitrile-derived amidoximes in and nitrilium ions …
Synthesis of novel pyrimido[4,5‐b]quinolines as potential anticancer agents and HER2 inhibitors
NSM Ibrahim, HH Kadry, AF Zaher… - Chemical Biology & …, 2023 - Wiley Online Library
A series of N‐arylpyrimido [4, 5‐b] quinolines 3a–e and 2‐aryl‐2, 3‐dihydropyrimido [4, 5‐b]
quinoline‐4 (1 H)‐ones 5a–e was designed and synthesized as potential anticancer agents …
quinoline‐4 (1 H)‐ones 5a–e was designed and synthesized as potential anticancer agents …
Synthesis of novel pyrimido[4,5‐b]quinoline derivatives as dual EGFR/HER2 inhibitors as anticancer agents
NSM Ibrahim, HH Kadry, AF Zaher… - Archiv der …, 2024 - Wiley Online Library
A series of novel N‐aryl‐5‐aryl‐6, 7, 8, 9‐tetrahydropyrimido [4, 5‐b] quinolin‐4‐amines 4a–
4l was synthesized as potential anticancer agents through Dimroth rearrangement reaction …
4l was synthesized as potential anticancer agents through Dimroth rearrangement reaction …
Boron-doped nanodiamonds as anticancer agents: En route to hyperthermia/thermoablation therapy
AM Vervald, SA Burikov, AM Scherbakov… - ACS Biomaterials …, 2020 - ACS Publications
Local targeted “inside-out” hyperthermia of tumors via nanoparticles is able to sensitize
tumor cells to chemotherapy, radiation therapy, gene therapy, immunotherapy, or other …
tumor cells to chemotherapy, radiation therapy, gene therapy, immunotherapy, or other …