Steroidal heterocyclic compounds constitute interesting and promising scaffolds for drug
discovery as they have displayed diverse chemical reactivity and several types of biological …

The rationale behind drug design is the strategic utilization of heterocyclic fragments with
specific physicochemical properties to form molecular targeted agents. Among the …

Exosomes are small vesicles which are produced by the cells and released into the
surrounding space. They can transfer biomolecules into recipient cells. The main goal of the …

An efficient and practical method has been developed for the synthesis of steroidal
imidazoheterocycles via cost-effective and environmentally benign FeCl3-catalyzed …

Heterocyclic derivatives of steroid hormones are potent anticancer agents, which are used in
the chemotherapy of breast and prostate cancers. Here, we describe a novel series of …

A flexible approach to previously unknown spirofused and linked 1, 3, 4-thiadiazine
derivatives of steroids with selective control of heterocyclization patterns is disclosed.(N …

A new series of Pyrimidine (A, D and F) and quinazoline (B, C and E) analogues of 1, 5-
benzodiazepines were prepared via its nitrile-derived amidoximes in and nitrilium ions …

A series of N‐arylpyrimido [4, 5‐b] quinolines 3a–e and 2‐aryl‐2, 3‐dihydropyrimido [4, 5‐b]
quinoline‐4 (1 H)‐ones 5a–e was designed and synthesized as potential anticancer agents …

A series of novel N‐aryl‐5‐aryl‐6, 7, 8, 9‐tetrahydropyrimido [4, 5‐b] quinolin‐4‐amines 4a–
4l was synthesized as potential anticancer agents through Dimroth rearrangement reaction …

Local targeted “inside-out” hyperthermia of tumors via nanoparticles is able to sensitize
tumor cells to chemotherapy, radiation therapy, gene therapy, immunotherapy, or other …