Active surveillance for prostate cancer: past, current, and future trends

II de Vos, HB Luiting, MJ Roobol - Journal of Personalized Medicine, 2023 - mdpi.com
In response to the rising incidence of indolent, low-risk prostate cancer (PCa) due to
increased prostate-specific antigen (PSA) screening in the 1990s, active surveillance (AS) …

A systematic review of focal ablative therapy for clinically localised prostate cancer in comparison with standard management options: limitations of the available …

AS Bates, J Ayers, N Kostakopoulos, T Lumsden… - European Urology …, 2021 - Elsevier
Context The clinical effectiveness of focal therapy (FT) for localised prostate cancer (PCa)
remains controversial. Objective To analyse the evidence base for primary FT for localised …

[HTML][HTML] Five-year outcomes of magnetic resonance imaging–based active surveillance for prostate cancer: a large cohort study

V Stavrinides, F Giganti, B Trock, S Punwani, C Allen… - European urology, 2020 - Elsevier
Background Although the use of multiparametric magnetic resonance imaging (mpMRI) in
active surveillance (AS) for prostate cancer is of increasing interest, existing data are derived …

Hyperpolarised 13C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer

N Sushentsev, MA McLean, AY Warren… - Nature …, 2022 - nature.com
Hyperpolarised magnetic resonance imaging (HP 13C-MRI) is an emerging clinical
technique to detect [1-13C] lactate production in prostate cancer (PCa) following intravenous …

Time series radiomics for the prediction of prostate cancer progression in patients on active surveillance

N Sushentsev, L Rundo, L Abrego, Z Li… - European …, 2023 - Springer
Serial MRI is an essential assessment tool in prostate cancer (PCa) patients enrolled on
active surveillance (AS). However, it has only moderate sensitivity for predicting …

Role of changes in magnetic resonance imaging or clinical stage in evaluation of disease progression for men with prostate cancer on active surveillance

GT Chesnut, EA Vertosick, N Benfante, DD Sjoberg… - European urology, 2020 - Elsevier
Background Active surveillance (AS) protocols rely on rectal examination, prostate-specific
antigen, imaging, and biopsy to identify disease progression. Objective To evaluate whether …

Comparative performance of MRI-derived PRECISE scores and delta-radiomics models for the prediction of prostate cancer progression in patients on active …

N Sushentsev, L Rundo, O Blyuss, T Nazarenko… - European …, 2022 - Springer
Objectives To compare the performance of the PRECISE scoring system against several
MRI-derived delta-radiomics models for predicting histopathological prostate cancer (PCa) …

[HTML][HTML] Active surveillance for prostate cancer

DK Shill, MJ Roobol, B Ehdaie, AJ Vickers… - Translational …, 2021 - ncbi.nlm.nih.gov
Many men diagnosed with localized prostate cancer can postpone definitive treatment
without raising their risk of metastasis or death from disease. Active surveillance (AS) is a …

The PRECISE recommendations for prostate MRI in patients on active surveillance for prostate cancer: A critical review

N Sanmugalingam, N Sushentsev… - American Journal of …, 2023 - Am Roentgen Ray Soc
The Prostate Cancer Radiological Estimation of Change in Sequential Evaluation
(PRECISE) recommendations were published in 2016 to standardize the reporting of MRI …

Genetic factors associated with prostate cancer conversion from active surveillance to treatment

Y Jiang, TJ Meyers, AA Emeka, LF Cooley… - Human Genetics and …, 2022 - cell.com
Men diagnosed with low-risk prostate cancer (PC) are increasingly electing active
surveillance (AS) as their initial management strategy. While this may reduce the side effects …