In the course of reviewing the anatomy and physiology of central nervous system (CNS)
serotonin [5= hydroxytryptamine(50HT)] in vertebrates, we focus on three major themes …

The role of serotonin (5-hydroxytryptamine; 5-HT) in the treatment of depressive and anxiety
disorders is underscored by the therapeutic action of selective 5-HT reuptake inhibitors …

Abstract The 5‐HT1A and 5‐HT1B receptors of serotonin play important roles as auto‐and
heteroreceptors controlling the release of serotonin itself and of other neurotransmitters …

Communication between nerve cells in the central nervous system (CNS) occurs at
synapses, which are specialized sites between the presynaptic nerve terminal and the …

G protein-gated inwardly rectifying potassium channels (Kir3/GirK) are important for
maintaining resting membrane potential, cell excitability and inhibitory neurotransmission …

Serotonin1A-receptors (5-HT1A-Rs) are important components of the 5-HT system in the
brain. As somatodendritic autoreceptors they control the activity of 5-HT neurons, and, as …

In low cerveau isolé transected rats, the effects of microiontophoretic application of putative
serotonin 5-HT 1A and 5-HT 1B agonists on the spontaneous firing rate of CA 1 pyramidal …

An intracerebral perfusion method, brain microdialysis, was used to assess changes of 5-
hydroxytryptamine (5-HT) release in the ventral hippocampus of the chloral hydrate …

Since the introduction of radioligand binding techniques in the 1970s, the number of sites
identified for 5-hydroxytryptamine (5-HT) has proliferated at a brisk rate. This trend has been …

Adaptive changes in the serotonergic system are generally believed to underlie the
therapeutic effectiveness of the azapirone anxiolytics and a variety of antidepressant drugs …