Due to the emergence of multidrug-resistant pathogens, it is necessary to develop options to
fight infections caused by these agents. Lactoferrin (Lf) is a cationic nonheme multifunctional …

Lactoferrin is an iron-binding glycoprotein present in most human exocrine fluids,
particularly breast milk. Lactoferrin is also released from neutrophil granules, and its …

Trp is unique among the amino acids since it is involved in many different types of
noncovalent interactions such as electrostatic and hydrophobic ones, but also in π-π, π …

In an era where the pipeline of new antibiotic development is drying up, the continuous rise
of multi-drug resistant (MDR) and extensively drug resistant (XDR) bacteria are genuine …

Most antimicrobial peptides (AMPs) damage the cell membrane of bacterial cells and induce
rapid leakage of the internal cell contents, which is a main cause of their bactericidal activity …

Osmotic pressure (Π) induces membrane tension in cells and lipid vesicles, which may affect
the activity of antimicrobial peptides (AMPs) by an unknown mechanism. We recently …

Lauric arginate (LAE), an amino acid-based cationic surfactant, has recently attracted great
attentions for applications in food preservation due to its antimicrobial properties. This work …

Conventional dendritic cells (cDCs) generate protective cytotoxic T lymphocyte (CTL)
responses against extracellular pathogens and tumors. This is achieved through a process …

Cell-penetrating peptides (CPPs) can translocate across plasma membranes to enter the
cytosol of eukaryotic cells without decreasing cell viability. We revealed the mechanism …

Living organisms maintain a resting membrane potential, which plays an important role in
various biophysical and biological processes. In the context of medical applications …