Why is COVID-19 more severe in patients with diabetes? The role of angiotensin-converting enzyme 2, endothelial dysfunction and the immunoinflammatory system

J Roberts, AL Pritchard, AT Treweeke… - Frontiers in …, 2021 - frontiersin.org
Meta-analyses have indicated that individuals with type 1 or type 2 diabetes are at increased
risk of suffering a severe form of COVID-19 and have a higher mortality rate than the non …

The emerging role of neutrophil extracellular traps in arterial, venous and cancer-associated thrombosis

Y Zhou, W Tao, F Shen, W Du, Z Xu… - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Neutrophils play a vital role in the formation of arterial, venous and cancer-related
thrombosis. Recent studies have shown that in a process known as NETosis, neutrophils …

Diabetic complications and prospective immunotherapy

L Reynolds, Z Luo, K Singh - Frontiers in Immunology, 2023 - frontiersin.org
The incidence of Diabetes Mellitus is increasing globally. Individuals who have been
burdened with diabetes for many years often develop complications as a result of …

[HTML][HTML] Thrombus composition and thrombolysis resistance in stroke

B Ho-Tin-Noé, JP Desilles, M Mazighi - Research and Practice in …, 2023 - Elsevier
A State of the Art lecture titled “Thrombus Composition and Thrombolysis Resistance in
Stroke” was presented at the ISTH Congress in 2022. Intravenous thrombolysis (IVT) …

Extracellular traps and the role in thrombosis

T Han, H Tang, C Lin, Y Shen, D Yan… - Frontiers in …, 2022 - frontiersin.org
Thrombotic complications pose serious health risks worldwide. A significant change in our
understanding of the pathophysiology of thrombosis has occurred since the discovery of …

Neutrophil extracellular traps affecting cardiovascular health in infectious and inflammatory diseases

M Thakur, B Evans, M Schindewolf, I Baumgartner… - Cells, 2021 - mdpi.com
Neutrophil extracellular traps (NETs) are web-like structures of decondensed extracellular
chromatin fibers and neutrophil granule proteins released by neutrophils. NETs participate …

Assessment of fibrinogen macromolecules interaction with red blood cells membrane by means of laser aggregometry, flow cytometry, and optical tweezers combined …

AN Semenov, AE Lugovtsov, EA Shirshin, BP Yakimov… - Biomolecules, 2020 - mdpi.com
An elevated concentration of fibrinogen in blood is a significant risk factor during many
pathological diseases, as it leads to an increase in red blood cells (RBC) aggregation …

[HTML][HTML] Fibrin clots from patients with acute-on-chronic liver failure are weaker than those from healthy individuals and patients with sepsis without underlying liver …

EG Driever, I Muntz, V Patel, J Adelmeijer… - Journal of Thrombosis …, 2023 - Elsevier
Background Previous studies identified decreased clot permeability, without differences in
fibrin fiber density in clots, from patients with cirrhosis compared with those from healthy …

The advances of blood clots used as biomaterials in regenerative medicine

E VanZweden, R Tolsma, V Hung, P Awad… - Regenerative …, 2022 - Taylor & Francis
The physiologic process of blood clot formation is well understood and occurs naturally in
the setting of tissue injury to achieve hemostasis and begin the process of wound healing …

[HTML][HTML] The citrullination-neutrophil extracellular trap axis in chronic diseases

M Maronek, R Gardlik - Journal of Innate Immunity, 2022 - karger.com
Citrullination of proteins is crucial for the formation of neutrophil extracellular traps (NETs)–
strands of nuclear DNA expulsed in the extracellular environment along with antimicrobial …