For the establishment of a successful infection, ie, long-term parasitism and a complete life
cycle, parasites use various diverse mechanisms and factors, which they may be inherently …

Lysosomal storage diseases (LSDs) comprise a group of inherited monogenic disorders
characterized by lysosomal dysfunctions due to undegraded substrate accumulation. They …

The intestinal parasite Entamoeba histolytica is one of the first protists for which a draft
genome sequence has been published. Although the genome is still incomplete, it is …

Hydrogenosomes and mitosomes are mitochondrion-related organelles in anaerobic/
microaerophilic eukaryotes with highly reduced and divergent functions. The full diversity of …

The epithelium represents the first and most extensive line of defence against pathogens,
toxins and pollutant agents in humans. In general, pathogens have developed strategies to …

Vesicular trafficking plays an important role in a virulence mechanism of the enteric
protozoan parasite Entamoeba histolytica as secreted and lysosomal cysteine protease (CP) …

Proteomic analysis of phagosomes isolated from Entamoeba histolytica by liquid
chromatography and mass spectrometry identified 85 proteins involved in surface …

Rab proteins are ubiquitous small GTP-binding proteins that form a highly conserved family
and regulate vesicular trafficking. Recent completion of the genome of the enteric protozoan …

Entamoeba histolytica is the cause of amebic colitis and liver abscess. This parasite induces
apoptosis in host cells and utilizes exposed ligands such as phosphatidylserine to ingest the …

To understand the roles of phosphoinositides [PtdIns] in phagocytosis of parasitic
eukaryotes, we examined the interaction of phosphatidylinositol‐3‐phosphate [PtdIns (3) P] …