Macrophages have been extensively used in the development of drug delivery systems, as
they can prolong the circulation and release of drugs, extend their half-life, increase their …

Glioblastoma is the most common primary brain tumor and has a dismal prognosis. The
development of central necrosis represents a tipping point in the evolution of these tumors …

Genomic alteration can reshape tumor microenvironment to drive tumor malignancy.
However, how PTEN deficiency influences microenvironment-mediated cell-cell interactions …

There are four subtypes of adenosine receptors (ARs), named A1, A2A, A2B and A3, all of
which are G protein-coupled receptors (GPCRs). Locally produced adenosine is a …

Molecular interaction networks lay the foundation for studying how biological functions are
controlled by the complex interplay of genes and proteins. Investigating perturbed processes …

Malignant neoplasms are characterized by poor therapeutic efficacy, high recurrence rate,
and extensive metastasis, leading to short survival. Previous methods for grouping …

Oral squamous cell carcinoma (OSCC) is the most prevalent form of oral and maxillofacial
malignancies, characterized by a low five-year survival rate primarily caused by invasion …

Background: Semaphorin 6b (SEMA6B) is a member of the semaphorin axon-guidance
family and has been demonstrated to both induce and inhibit tumor progression. However …

Glioma is the most prevalent invasive primary tumor of the central nervous system. Glioma
cells can spread and infiltrate into normal surrounding brain tissues. Despite the standard …

Background Glioblastomas (GBM) are rapidly progressive, nearly uniformly fatal brain
tumors. Proteomic analysis represents an opportunity for noninvasive GBM classification …