Near-infrared spectroscopy (NIRS) is used to monitor regional cerebral oxygenation (rScO2)
during cardiac surgery but is less established during non-cardiac surgery. This systematic …

The British physician George Oliver was among the first to investigate the vasoactive
properties of the adrenal gland. In 1893, using his son as a research subject, Dr Oliver …

There is a growing emphasis being placed on the potential for cuffless blood pressure (BP)
estimation through modelling of morphological features from the photoplethysmogram (PPG) …

Background Carbonic anhydrases catalyze CO2/HCO3–buffer reactions with implications for
effective H+ mobility, pH dynamics, and cellular acid–base sensing. Yet, the integrated …

Background Postoperative hypotension and hypertension are frequent events associated
with increased risk of adverse outcomes. However, proper assessment and management is …

Background Studies in anesthetized patients suggest that phenylephrine reduces regional
cerebral oxygen saturation compared with ephedrine. The present study aimed to quantify …

Induction of general anesthesia frequently induces arterial hypotension, which is often
treated with a vasopressor, such as phenylephrine. As a pure α-agonist, phenylephrine is …

BACKGROUND: Phenylephrine infusion is the current first-line choice for prevention of
spinal hypotension during cesarean delivery. The optimal dosage regimen is still …

Stable intraoperative haemodynamics are associated with improved outcome and even
short periods of instability are associated with an increased risk of complications. During …

Purpose Understanding cardiovascular physiology should help clinicians to understand the
purpose of fluid and drug management during the perioperative period. The purpose of this …