Roles and mechanisms of exosomal non-coding RNAs in human health and diseases
C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications
Exosomes are endosome-derived nanovesicles involved in cellular communication. They
are natural nanocarriers secreted by various cells, making them suitable candidates for …
are natural nanocarriers secreted by various cells, making them suitable candidates for …
Mesenchymal stem cell-derived exosomes: applications in regenerative medicine
Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …
are then released into the extracellular space through a merging of the multivesicular body …
Metal-polyDNA nanoparticles reconstruct osteoporotic microenvironment for enhanced osteoporosis treatment
X Liu, F Li, Z Dong, C Gu, D Mao, J Chen, L Luo… - Science …, 2023 - science.org
Current clinical approaches to osteoporosis primarily target osteoclast biology, overlooking
the synergistic role of bone cells, immune cells, cytokines, and inorganic components in …
the synergistic role of bone cells, immune cells, cytokines, and inorganic components in …
[HTML][HTML] Breast cancer exosomes contribute to pre-metastatic niche formation and promote bone metastasis of tumor cells
X Yuan, N Qian, S Ling, Y Li, W Sun, J Li, R Du… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Breast cancer preferentially develops osteolytic bone metastasis, which makes
patients suffer from pain, fractures and spinal cord compression. Accumulating evidences …
patients suffer from pain, fractures and spinal cord compression. Accumulating evidences …
Recent advancements in the use of exosomes as drug delivery systems
EJ Bunggulawa, W Wang, T Yin, N Wang… - Journal of …, 2018 - Springer
Extracellular vesicles (EVs) are the substances that are released by most types of cells and
have an important role in cell to cell communication. Among the most highly researched EVs …
have an important role in cell to cell communication. Among the most highly researched EVs …
Osteoblast–osteoclast interactions
X Chen, Z Wang, N Duan, G Zhu… - Connective tissue …, 2018 - Taylor & Francis
Bone homeostasis depends on the resorption of bones by osteoclasts and formation of
bones by the osteoblasts. Imbalance of this tightly coupled process can cause diseases …
bones by the osteoblasts. Imbalance of this tightly coupled process can cause diseases …
[HTML][HTML] LncRNA MALAT1 shuttled by bone marrow-derived mesenchymal stem cells-secreted exosomes alleviates osteoporosis through mediating microRNA-34c …
X Yang, J Yang, P Lei, T Wen - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) have emerged as promising novel modulators during
osteogenesis in mesenchymal stem cells (MSCs). Enhanced SATB2 has been …
osteogenesis in mesenchymal stem cells (MSCs). Enhanced SATB2 has been …
Osteoblast differentiation and signaling: established concepts and emerging topics
M Ponzetti, N Rucci - International Journal of Molecular Sciences, 2021 - mdpi.com
Osteoblasts, the cells that build up our skeleton, are remarkably versatile and important cells
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …
that need tight regulation in all the phases of their differentiation to guarantee proper skeletal …
Bone‐targeted exosomes: strategies and applications
J Wang, X Li, S Wang, J Cui, X Ren… - Advanced healthcare …, 2023 - Wiley Online Library
As the global population ages, bone‐related diseases have increasingly become a major
social problem threatening human health. Exosomes, as natural cell products, have been …
social problem threatening human health. Exosomes, as natural cell products, have been …