Mitochondria and metabolic transitions in cardiomyocytes: lessons from development for stem cell-derived cardiomyocytes
JC Garbern, RT Lee - Stem Cell Research & Therapy, 2021 - Springer
Current methods to differentiate cardiomyocytes from human pluripotent stem cells (PSCs)
inadequately recapitulate complete development and result in PSC-derived cardiomyocytes …
inadequately recapitulate complete development and result in PSC-derived cardiomyocytes …
Concurrent diabetes and heart failure: interplay and novel therapeutic approaches
QG Karwi, KL Ho, S Pherwani, EB Ketema… - Cardiovascular …, 2022 - academic.oup.com
Diabetes mellitus increases the risk of developing heart failure, and the co-existence of both
diseases worsens cardiovascular outcomes, hospitalization, and the progression of heart …
diseases worsens cardiovascular outcomes, hospitalization, and the progression of heart …
LncRNA SNHG11 promotes proliferation, migration, apoptosis, and autophagy by regulating hsa-miR-184/AGO2 in HCC
W Huang, F Huang, Z Lei, H Luo - OncoTargets and therapy, 2020 - Taylor & Francis
Background The most common malignant tumor of the digestive system is HCC. However,
the mechanism and pathogenesis of HCC occurrence and progress are still unknown …
the mechanism and pathogenesis of HCC occurrence and progress are still unknown …
LCZ696 protects against diabetic cardiomyopathy-induced myocardial inflammation, ER stress, and apoptosis through inhibiting AGEs/NF-κB and PERK/CHOP …
The present study is designed to determine the effect of LCZ696 on DCM in rats and
investigate the underlying mechanism involved. Diabetes was induced by feeding rats with a …
investigate the underlying mechanism involved. Diabetes was induced by feeding rats with a …
Clinical relevance of lncRNA and mitochondrial targeted antioxidants as therapeutic options in regulating oxidative stress and mitochondrial function in vascular …
Metabolic imbalances and persistent hyperglycemia are widely recognized as driving forces
for augmented cytosolic and mitochondrial reactive oxygen species (ROS) in diabetes …
for augmented cytosolic and mitochondrial reactive oxygen species (ROS) in diabetes …
LncRNA-MIAT-mediated miR-214-3p silencing is responsible for IL-17 production and cardiac fibrosis in diabetic cardiomyopathy
Y Qi, H Wu, C Mai, H Lin, J Shen, X Zhang… - Frontiers in cell and …, 2020 - frontiersin.org
As an important complication of diabetes mellitus, diabetic cardiomyopathy (DCM) is
characterized by a silent development in its earlier stage and a deficient cardiomyocyte …
characterized by a silent development in its earlier stage and a deficient cardiomyocyte …
Long noncoding RNA MAPKAPK5-AS1 promotes colorectal cancer progression by cis-regulating the nearby gene MK5 and acting as a let-7f-1-3p sponge
T Yang, WC Chen, PC Shi, MR Liu, T Jiang… - Journal of Experimental …, 2020 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) are considered critical regulators in
cancers; however, the clinical significance and mechanisms of MAPKAPK5-AS1 (hereinafter …
cancers; however, the clinical significance and mechanisms of MAPKAPK5-AS1 (hereinafter …
Recent insight on the non-coding RNAs in mesenchymal stem cell-derived exosomes: regulatory and therapeutic role in regenerative medicine and tissue …
Advances in the field of regenerative medicine and tissue engineering over the past few
decades have paved the path for cell-free therapy. Numerous stem cell types, including …
decades have paved the path for cell-free therapy. Numerous stem cell types, including …
Unravelling lncRNA mediated gene expression as potential mechanism for regulating secondary metabolism in Citrus limon
Plant long non-coding RNAs (lncRNAs) are emerging as important regulators of gene
expression through various mechanisms viz. binding to double-stranded DNA (dsDNA) …
expression through various mechanisms viz. binding to double-stranded DNA (dsDNA) …
HMGCS2 silencing attenuates high glucose-induced in vitro diabetic cardiomyopathy by increasing cell viability, and inhibiting apoptosis, inflammation, and oxidative …
D Chen, X Ruan, Y Liu, Y He - Bioengineered, 2022 - Taylor & Francis
Diabetic cardiomyopathy (DCM) is a diabetic mellitus-related complications and progression
of DCM may eventually lead to heart failure, while mechanisms related to DCM …
of DCM may eventually lead to heart failure, while mechanisms related to DCM …